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一家三级癌症中心骨与软组织疾病管理组收治患者的流行病学数据及病例负荷谱。

Epidemiological data and case load spectrum of patients presenting to bone and soft tissue disease management group at a tertiary cancer center.

作者信息

Gulia A, Puri A, Chorge S, Panda P K

机构信息

Orthopedic Oncology Services, Department of Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India.

出版信息

Indian J Cancer. 2016 Apr-Jun;53(2):333-338. doi: 10.4103/0019-509X.197734.

Abstract

INTRODUCTION AND BACKGROUND

This study was conducted to know the spectrum and number of bone and soft tissue (BST) tumors presenting to our institute. We needed to assess the gap between the number of patients seen and infrastructure available, and based on this information, help formulate guidelines for optimum utilization of resources and to provide best possible evidence-based cancer care.

SETTINGS AND DESIGNS

This is a prospective observational study (epidemiological).

MATERIALS AND METHODS

This study included all new patients seen in BST-disease management group (DMG) in the year 2010. An audit form was devised to capture all the relevant information. A comparison of our data with other national and international studies was also done.

RESULTS

Out of total 31,951 new patients registered at our institute, 2007 patients availed BST-DMG services. Sixty percent were bone tumors and 36% were soft tissue tumors. In bone tumor, 66% were malignant, 15% were benign, and 19% were non-neoplastic. Osteosarcoma (43%) was the most common malignant tumor followed by primitive neuroectodermal tumor/Ewing's (27%) and chondrosarcoma (11%). Giant cell tumor was the most common benign bone tumor. Eighty-one percent of all soft tissue lesions were malignant, of which 75% were of mesenchymal origin and 25% were of cutaneous origin.

CONCLUSION

This is an attempt to document the epidemiology of musculoskeletal tumors presenting to our institution while guiding the institute to frame and implement disease-specific protocols and generate further research questions. Continued data collection and follow-up can provide valuable information on long-term survival and treatment-related toxicities. This data (within limitations) may be extrapolated to national level to identify the need for infrastructure and human resources.

摘要

引言与背景

本研究旨在了解我院收治的骨与软组织(BST)肿瘤的种类及数量。我们需要评估就诊患者数量与现有基础设施之间的差距,并基于此信息,协助制定资源优化利用指南,以提供尽可能最佳的循证癌症护理。

设置与设计

这是一项前瞻性观察性(流行病学)研究。

材料与方法

本研究纳入了2010年在BST疾病管理组(DMG)就诊的所有新患者。设计了一份审核表以收集所有相关信息。还将我们的数据与其他国内和国际研究进行了比较。

结果

在我院登记的31951名新患者中,有2007名患者接受了BST-DMG服务。其中60%为骨肿瘤,36%为软组织肿瘤。在骨肿瘤中,66%为恶性,15%为良性,19%为非肿瘤性。骨肉瘤(43%)是最常见的恶性肿瘤,其次是原始神经外胚层肿瘤/尤因肉瘤(27%)和软骨肉瘤(11%)。骨巨细胞瘤是最常见的良性骨肿瘤。所有软组织病变中81%为恶性,其中75%起源于间叶组织,25%起源于皮肤。

结论

本研究旨在记录我院肌肉骨骼肿瘤的流行病学情况,同时指导我院制定和实施针对特定疾病的方案,并提出进一步的研究问题。持续的数据收集和随访可为长期生存及治疗相关毒性提供有价值的信息。这些数据(在一定范围内)可外推至国家层面,以确定对基础设施和人力资源的需求。

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