Yücetürk Güven, Sabah Dündar, Keçeci Burçin, Kara Ahmet Duran, Yalçinkaya Selçuk
Department of Orthopaedics and Traumatology, Medical Faculty of Ege University, İzmir, Turkey.
Acta Orthop Traumatol Turc. 2011;45(3):135-43. doi: 10.3944/AOTT.2011.2504.
Multidisciplinary approach is a necessity for the appropriate diagnosis and treatment of bone and soft tissue tumors. The Ege University Musculoskeletal Tumor Council offers consultation services to other hospitals in the Aegean region. Since 1988 the Council has met weekly and spent approximately 1,500 hours evaluating almost 6,000 patients with suspected skeletal system tumors. Our objective was to present the data obtained from this patient group.
A total of 5,658 patients, suspected to have a musculoskeletal tumor, were evaluated retrospectively. Multiple records of the patients due to multiple attendance to the Council were excluded. The prevalance of the bone and soft tissue tumors in these patients were analysed.
Malignant mesenchymal tumors accounted for 39.7% of the total patients, benign tumors for 17%, tumor-like lesions for 17.8% and metastatic carsinomas for 8.6%. Malignant bone tumors were 50.2% and malignant soft tissue tumors were 49.8% of all the sarcomas. Among the malignant bone tumors the most common was osteosarcomas at a rate of 33.6%, followed by Ewing-PNET at 25.5%, chondrosarcomas at 19.4% and haematopoietic tumors at 17.6%. Pleomorphic sarcomas (24.5%), liposarcoma (16.4%), synovial sarcoma (13%) and undifferential sarcomas (8.8%) were the most common types of malignant sof tissue tumors. Benign soft tissue tumors (48%), benign cartilage tumors (28%), giant cell tumor (15%) and osteogenic tumors (9%) were found among the benign tumors. Hemangioma, lipoma, agressive fibromatosis, enchondroma, solitary chondroma and osteoid osteoma were the most common tumors in their groups. Lung (27%), breast (24%), gastrointestinal system (10.5%) and kidney (8.2%) carcinomas were the most common primary sites of the bone metastasis.
Turkey still lacks a comprehensive series indicating the incidence and diagnostic distribution of bone and soft tissue tumors. The presented data would add to our knowledge on the specific rates of the bone and soft tissue tumors in Aegean region.
多学科方法对于骨骼和软组织肿瘤的恰当诊断与治疗必不可少。伊兹密尔埃杰大学肌肉骨骼肿瘤委员会为爱琴海地区的其他医院提供咨询服务。自1988年以来，该委员会每周召开会议，花费约1500小时评估近6000例疑似骨骼系统肿瘤的患者。我们的目的是呈现从该患者群体中获得的数据。
对总共5658例疑似患有肌肉骨骼肿瘤的患者进行回顾性评估。排除因多次参加委员会而有多个记录的患者。分析这些患者中骨骼和软组织肿瘤的患病率。
恶性间叶性肿瘤占患者总数的39.7%，良性肿瘤占17%，肿瘤样病变占17.8%，转移性癌占8.6%。恶性骨肿瘤占所有肉瘤的50.2%，恶性软组织肿瘤占49.8%。在恶性骨肿瘤中，最常见的是骨肉瘤，占比33.6%，其次是尤因肉瘤-原始神经外胚层肿瘤，占25.5%，软骨肉瘤占19.4%，造血系统肿瘤占17.6%。多形性肉瘤（24.5%）、脂肪肉瘤（16.4%）、滑膜肉瘤（13%）和未分化肉瘤（8.8%）是最常见的恶性软组织肿瘤类型。良性肿瘤中发现良性软组织肿瘤（48%）、良性软骨肿瘤（28%）、骨巨细胞瘤（15%）和成骨性肿瘤（9%）。血管瘤、脂肪瘤、侵袭性纤维瘤病、内生软骨瘤、孤立性软骨瘤和骨样骨瘤是各自类别中最常见的肿瘤。肺癌（27%）、乳腺癌（24%）、胃肠道系统癌（10.5%）和肾癌（8.2%）是骨转移最常见的原发部位。
土耳其仍然缺乏一个全面的系列数据来表明骨骼和软组织肿瘤的发病率及诊断分布情况。所呈现的数据将增加我们对爱琴海地区骨骼和软组织肿瘤特定发病率的了解。
