黑海中部地区骨与软组织肿瘤的分布及评估

Distribution and evaluation of bone and soft tissue tumors in the middle Black Sea Region.

作者信息

Dabak Nevzat, Cıraklı Alper, Gülman Birol, Selçuk Mustafa Bekir, Barış Sancar

机构信息

Department of Orthopedics and Traumatology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.

Department of Orthopedics and Traumatology, Suluova State Hospital, Amasya, Turkey.

出版信息

Acta Orthop Traumatol Turc. 2014;48(1):17-24. doi: 10.3944/AOTT.2014.3013.

DOI:10.3944/AOTT.2014.3013

PMID:24643095

Abstract

OBJECTIVE

The aim of this study was to evaluate the characteristics of bone and soft tissue tumors operated on at the Department of Orthopedics and Traumatology at Ondokuz Mayıs University Faculty of Medicine Hospital between January 1987 and January 2012.

METHODS

This descriptive study retrospectively evaluated 1,925 patients hospitalized with a preliminary diagnosis of tumor. Patients were analyzed for age, gender, tumor incidence and localization. Three hundred and forty-nine patients found to have non-tumor causes. The 94 patients discharged at their own request or deceased during follow-up were not included in the tumor group.

RESULTS

Of the 1,482 (76.9%) patients diagnosed with tumor, 687 (46.4%) were bone tumors, 586 (39.5%) soft tissue tumors and 209 (14.1%) metastatic tumors. The most common benign bone tumor was osteochondroma (118; 25%), followed by enchondroma (68; 14.4%) and giant cell tumor (59; 12.5%), and the most common malignant bone tumor was osteosarcoma (58; 27%), followed by chondrosarcoma (36; 16.7%) and Ewing's sarcoma (33; 15.3%). The most common benign soft tissue tumor was cystic hygroma (96; 22%), followed by lipoma (75; 17.2%) and hemangioma (52; 11.9%), and the most common malignant soft tissue tumors were pleomorphic cell tumor (29; 19.3%) and liposarcoma (29; 19.3%), followed by pleomorphic undifferentiated sarcoma (21; 14%). Seventy (33.5%) of the metastatic tumors were of pulmonary origin, 36 (17.2%) were of breast origin and the primary site of the tumor was not clearly determined in 58 (27.8%) patients.

CONCLUSION

The distribution of bone and soft tissue tumors appear to have certain characteristics but can show regional differences. We believe that the establishment of a larger series through the collection of these types of studies from centers in which bone and soft tissue tumor surgery is performed will provide important information on the epidemiological features of bone and soft tissue tumors.

摘要

目的

本研究旨在评估1987年1月至2012年1月间在翁多库兹迈伊斯大学医学院医院骨科与创伤科接受手术的骨与软组织肿瘤的特征。

方法

这项描述性研究回顾性评估了1925例初步诊断为肿瘤的住院患者。分析患者的年龄、性别、肿瘤发病率及部位。349例患者被发现存在非肿瘤性病因。94例因个人要求出院或在随访期间死亡的患者未纳入肿瘤组。

结果

在1482例（76.9%）被诊断为肿瘤的患者中，687例（46.4%）为骨肿瘤，586例（39.5%）为软组织肿瘤，209例（14.1%）为转移性肿瘤。最常见的良性骨肿瘤是骨软骨瘤（118例；25%），其次是内生软骨瘤（68例；14.4%）和骨巨细胞瘤（59例；12.5%），最常见的恶性骨肿瘤是骨肉瘤（58例；27%），其次是软骨肉瘤（36例；16.7%）和尤因肉瘤（33例；15.3%）。最常见的良性软组织肿瘤是囊性水瘤（96例；22%），其次是脂肪瘤（75例；17.2%）和血管瘤（52例；11.9%），最常见的恶性软组织肿瘤是多形性细胞肿瘤（29例；19.3%）和脂肪肉瘤（29例；19.3%），其次是多形性未分化肉瘤（21例；14%）。70例（33.5%）转移性肿瘤起源于肺部，36例（17.2%）起源于乳腺，58例（27.8%）患者肿瘤的原发部位未明确确定。