Fletcher C D, Theaker J M
Department of Histopathology, St Thomas's Hospital Medical School, London, UK.
Histopathology. 1989 Sep;15(3):249-56. doi: 10.1111/j.1365-2559.1989.tb03075.x.
Neural tumours composed solely of Pacinian corpuscles or showing focal Pacinian differentiation are extremely rare and have only occasionally been reported in the literature. All such lesions to date have been benign. Three lesions are described herein which presented as painful digital masses in middle-aged adults and which were composed of abnormal aggregates of morphologically mature Pacinian corpuscles and intervening small nerves. Only five similar cases have been previously recorded. Possible pathogenetic mechanisms of this unusual hyperplastic phenomenon are discussed.
仅由帕西尼小体组成或显示局灶性帕西尼分化的神经肿瘤极为罕见，文献中仅有零星报道。迄今为止，所有此类病变均为良性。本文描述了三例病变，表现为中年成年人手指疼痛性肿块，由形态成熟的帕西尼小体和其间的小神经异常聚集而成。此前仅记录过五例类似病例。本文还讨论了这种不寻常增生现象可能的发病机制。
