Condén Emelie, Rosenblad Andreas, Wagner Philippe, Leppert Jerzy, Ekselius Lisa, Åslund Cecilia
1 Centre for Clinical Research, Uppsala University, Sweden.
2 School of Health, Care and Social Welfare, Malardalen University, Sweden.
Eur J Prev Cardiol. 2017 Mar;24(5):522-533. doi: 10.1177/2047487316687427. Epub 2017 Jan 10.
Background Type D personality refers to a combination of simultaneously high levels of negative affectivity and social inhibition. The present study aimed to examine whether type D personality was independently associated with recurrent myocardial infarction or all-cause mortality in post-acute myocardial infarction patients, using any of the previously proposed methods for measuring type D personality. Design This was a prospective cohort study. Methods Utilising data from the Västmanland Myocardial Infarction Study, 946 post-acute myocardial infarction patients having data on the DS14 instrument used to measure type D personality were followed-up for recurrent myocardial infarction and all-cause mortality until 9 December 2015. Data were analysed using Cox regression, adjusted for established risk factors. Results In total, 133 (14.1%) patients suffered from type D personality. During a mean follow-up time for recurrent myocardial infarction of 5.7 (3.2) years, 166 (17.5%) patients were affected by recurrent myocardial infarction, of which 26 (15.7%) had type D personality, while during a mean follow-up time for all-cause mortality of 6.3 (2.9) years, 321 (33.9%) patients died, of which 42 (13.1%) had type D personality. After adjusting for established risk factors, type D personality was not significantly associated with recurrent myocardial infarction or all-cause mortality using any of the previously proposed methods for measuring type D personality. A weak association was found between the social inhibition part of type D personality and a decreased risk of all-cause mortality, but this association was not significant after taking missing data into account in a multiple imputation analysis. Conclusions No support was found for type D personality being independently associated with recurrent myocardial infarction or all-cause mortality in post-acute myocardial infarction patients, using any of the previously proposed methods for measuring type D personality.
背景 D 型人格是指同时具有高水平消极情感和社交抑制的一种人格组合。本研究旨在使用任何先前提出的测量 D 型人格的方法，检验 D 型人格是否与急性心肌梗死后患者的复发性心肌梗死或全因死亡率独立相关。
设计 这是一项前瞻性队列研究。
方法 利用韦斯特曼兰心肌梗死研究的数据，对 946 例使用 DS14 工具测量 D 型人格且有相关数据的急性心肌梗死后患者进行随访，观察复发性心肌梗死和全因死亡率，直至 2015 年 12 月 9 日。数据采用 Cox 回归分析，并对已确定的危险因素进行校正。
结果 共有 133 例（14.1%）患者为 D 型人格。在复发性心肌梗死的平均随访时间 5.7（3.2）年中，166 例（17.5%）患者发生复发性心肌梗死，其中 26 例（15.7%）为 D 型人格；在全因死亡率的平均随访时间 6.3（2.9）年中，321 例（33.9%）患者死亡，其中 42 例（13.1%）为 D 型人格。在对已确定的危险因素进行校正后，使用任何先前提出的测量 D 型人格的方法，D 型人格与复发性心肌梗死或全因死亡率均无显著相关性。发现 D 型人格的社交抑制部分与全因死亡率降低之间存在微弱关联，但在多重填补分析中考虑缺失数据后，这种关联并不显著。
结论 使用任何先前提出的测量 D 型人格的方法，均未发现 D 型人格与急性心肌梗死后患者的复发性心肌梗死或全因死亡率独立相关。
