Kellogg Nancy D, Melville John D, Lukefahr James L, Nienow Shalon M, Russell Edward L
Division of Child Abuse Pediatrics, Medical University of South Carolina, Charleston, SC.
University of New Mexico, Albuquerque, NM.
Pediatr Emerg Care. 2018 Nov;34(11):761-766. doi: 10.1097/PEC.0000000000001014.
The aim of this study was to describe the use of a nucleic acid amplification test in detecting genital and extragenital Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) in children and adolescents assessed for sexual abuse/assault.
The charts of children aged 0 to 17 years, consecutively evaluated for sexual victimization, in emergency department and outpatient settings were reviewed. Data extracted included age, sex, type of sexual contact, anogenital findings, previous sexual contact, toxicology results, and sites tested for NG and CT.
Of the 1319 patients who were tested, 579 were tested at more than 1 site, and 120 had at least 1 infected site. Chlamydia trachomatis was identified in 104 patients, and NG was found in 33. In bivariate analysis, a positive test was associated with female sex, age older than 11 years, previous sexual contact, acute or healed genital injury, drug/alcohol intoxication, and examination within 72 hours of sexual contact. Fifty-one patients had positive anal tests, and 24 had positive oral tests. More than 75% of patients with positive extragenital tests had additional positive tests or anogenital injury. Most with a positive anal (59%) or oral (77%) test did not report that the assailant's genitals came into contact with that site.
Positive tests for NG and CT in patients evaluated for sexual victimization may represent infection from sexual contact, contiguous spread of infection, or the presence of infected assailant secretions. Relying on patient reports of symptoms, or types of sexual contact, to determine need for testing may miss NG and CT infections in patients evaluated for sexual victimization.
本研究旨在描述核酸扩增试验在检测因性虐待/性侵犯接受评估的儿童和青少年的生殖器及生殖器外淋病奈瑟菌(NG)和沙眼衣原体(CT)中的应用。
回顾了在急诊科和门诊连续接受性侵害评估的0至17岁儿童的病历。提取的数据包括年龄、性别、性接触类型、肛门生殖器检查结果、既往性接触、毒理学结果以及检测NG和CT的部位。
在1319名接受检测的患者中,579人在多个部位进行了检测,120人至少有1个感染部位。104名患者检测出沙眼衣原体,33名患者检测出淋病奈瑟菌。在双变量分析中,检测呈阳性与女性、年龄大于11岁、既往性接触、急性或已愈合的生殖器损伤、药物/酒精中毒以及性接触后72小时内进行检查有关。51名患者肛门检测呈阳性,24名患者口腔检测呈阳性。生殖器外检测呈阳性的患者中,超过75%有其他阳性检测结果或肛门生殖器损伤。大多数肛门(59%)或口腔(77%)检测呈阳性的患者并未报告袭击者的生殖器与该部位有接触。
因性侵害接受评估的患者中NG和CT检测呈阳性可能代表性接触感染、感染的连续传播或存在感染袭击者的分泌物。依靠患者的症状报告或性接触类型来确定检测需求可能会遗漏因性侵害接受评估的患者中的NG和CT感染。