Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Cancer Cell. 2017 Jan 9;31(1):2-4. doi: 10.1016/j.ccell.2016.12.007.
Effective cancer therapy requires that a cancer be more susceptible to a treatment than are the essential tissues in the body. A paper by Sarosiek et al. in this issue now shows that, unlike those of cancer cells, mitochondria in many tissues in adults are in an apoptosis-resistant state.
有效的癌症治疗需要使癌症比体内的基本组织更容易受到治疗的影响。Sarosiek 等人在本期杂志上发表的一篇论文表明,与癌细胞不同,成年人体内许多组织的线粒体处于抗细胞凋亡状态。