MGH Cancer Center & Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Curr Biol. 2017 Jan 9;27(1):R33-R35. doi: 10.1016/j.cub.2016.11.025.
The ATR kinase is a master regulator of replication stress responses. Four new studies show that the protein ETAA1 is an important activator of ATR in human cells, providing insights into how the ATR pathway reacts to replication stress.
ATR 激酶是复制应激反应的主要调节因子。四项新研究表明，蛋白 ETAA1 是人类细胞中 ATR 的重要激活因子，为了解 ATR 途径如何对复制应激做出反应提供了线索。
