Kim Jae-Min, Kang Hee-Ju, Bae Kyung-Yeol, Kim Sung-Wan, Shin Il-Seon, Hong Young Joon, Ahn Youngkeun, Jeong Myung Ho, Yoon Jin-Sang
Departments of Psychiatry, Chonnam National University Medical School, Republic of Korea.
Departments of Psychiatry, Chonnam National University Medical School, Republic of Korea.
J Affect Disord. 2017 Mar 1;210:319-322. doi: 10.1016/j.jad.2017.01.002. Epub 2017 Jan 3.
This study investigated the effects of sleep disturbance evaluated within 2 weeks after patients developed acute coronary syndrome (ACS) on depressive disorders at the 1-year follow-up.
A total of 1152 patients were recruited consecutively within 2 weeks after a confirmed ACS episode, and 828 were followed 1 year later. Sleep disturbances were evaluated at baseline using the Leeds Sleep Evaluation Questionnaire (LSEQ), which subjectively assesses four sleep factors. At both examinations, depressive disorders were diagnosed using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Baseline covariates included sociodemographic data, characteristics of depression, cardiovascular risk factors, and current cardiac status.
Almost all aspects of the sleep disturbance and the increase in their worst state evaluated by the LSEQ within 2 weeks of ACS predicted both incident and persistent depressive disorders at the 1-year follow-up independent of covariates related to sleep problems.
Data on sleep disturbance were obtained only by subjective reports.
A simple evaluation of sleep disturbance in patients who recently developed ACS in a hospital setting could help predict depression at the chronic phase.
本研究调查了急性冠状动脉综合征（ACS）患者发病后2周内评估的睡眠障碍对1年随访时抑郁症的影响。
在确诊ACS发作后的2周内连续招募了1152名患者，1年后对828名患者进行随访。使用利兹睡眠评估问卷（LSEQ）在基线时评估睡眠障碍，该问卷主观评估四个睡眠因素。在两次检查中，均使用《精神疾病诊断与统计手册》第四版诊断抑郁症。基线协变量包括社会人口统计学数据、抑郁特征、心血管危险因素和当前心脏状况。
ACS发病后2周内通过LSEQ评估的睡眠障碍几乎所有方面及其最严重状态的增加，均可预测1年随访时的新发和持续性抑郁症，且独立于与睡眠问题相关的协变量。
睡眠障碍数据仅通过主观报告获得。
在医院环境中对近期发生ACS的患者进行简单的睡眠障碍评估，有助于预测慢性期的抑郁症。
