Department of Psychiatry, Chonnam National University Medical School, 160 Baekseoro, Dong-gu, Gwangju 501-757, Republic of Korea.
Department of Cardiology, Chonnam National University Medical School, Republic of Korea.
Psychiatry Res. 2017 Sep;255:328-331. doi: 10.1016/j.psychres.2017.06.003.
This study investigated the impact of anxiety evaluated within 2 weeks of an acute coronary syndrome (ACS) episode on depressive outcomes at a 1-year follow-up assessment. In 828 ACS patients, anxiety was determined by Hospital Anxiety and Depression Scale-anxiety subscale at baseline, and DSM-IV depressive disorders and depressive symptoms were evaluated both at baseline and follow-up. Anxiety at baseline was significantly associated with depressive disorder at the follow-up and less improvement in depressive symptoms over 1-year. Anxiety had negative longitudinal impacts on depressive outcomes of ACS, and therefore evaluation of anxiety could be recommended in recently developed ACS patients.
本研究调查了急性冠状动脉综合征（ACS）发作后 2 周内评估的焦虑对 1 年随访时抑郁结局的影响。在 828 例 ACS 患者中，焦虑通过基线时的医院焦虑抑郁量表焦虑分量表确定，在基线和随访时均评估 DSM-IV 抑郁障碍和抑郁症状。基线时的焦虑与随访时的抑郁障碍显著相关，并且在 1 年内抑郁症状的改善程度较低。焦虑对 ACS 的抑郁结局有负面的纵向影响，因此建议对新确诊的 ACS 患者进行焦虑评估。
