Guo Ruru, Shen Wencui, Su Chang, Jiang Shaoyun, Wang Jiantao
Department of Ophthalmology, Tianjin Medical University Eye Hospital and Eye Institute, Tianjin, China.
Ophthalmic Res. 2017;57(3):194-199. doi: 10.1159/000450957. Epub 2017 Jan 11.
Small RNA (microRNA or miRNA) is a kind of small noncoding single-stranded RNA that regulates complementary mRNA at the posttranscriptional level in eukaryotic organisms. As important regulatory factors, miRNAs play an important role in the occurrence and development of glaucoma and widely participate in regulating biological processes of glaucoma-related genes. This article reviews the connection between the aqueous humor, trabecular meshwork, the apoptosis of retinal ganglion cells, and miRNA.
小RNA（微小RNA或miRNA）是一种小的非编码单链RNA，在真核生物中，它在转录后水平调控互补mRNA。作为重要的调控因子，miRNA在青光眼的发生和发展中发挥重要作用，并广泛参与调节青光眼相关基因的生物学过程。本文综述了房水、小梁网、视网膜神经节细胞凋亡与miRNA之间的联系。
