Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha 410013, China.
Int J Mol Sci. 2023 Oct 19;24(20):15377. doi: 10.3390/ijms242015377.
Glaucoma is similar to a neurodegenerative disorder and leads to global irreversible loss of vision. Despite extensive research, the pathophysiological mechanisms of glaucoma remain unclear, and no complete cure has yet been identified for glaucoma. Recent studies have shown that microRNAs can serve as diagnostic biomarkers or therapeutic targets for glaucoma; however, there are few bibliometric studies that focus on using microRNAs in glaucoma research. Here, we have adopted a bibliometric analysis in the field of microRNAs in glaucoma research to manifest the current tendencies and research hotspots and to present a visual map of the past and emerging tendencies in this field. In this study, we retrieved publications in the Web of Science database that centered on this field between 2007 and 2022. Next, we used VOSviewer, CiteSpace, Scimago Graphica, and Microsoft Excel to present visual representations of a co-occurrence analysis, co-citation analysis, tendencies, hotspots, and the contributions of authors, institutions, journals, and countries/regions. The United States was the main contributor. has published the most articles in this field. Over the past 15 years, there has been exponential growth in the number of publications and citations in this field across various countries, organizations, and authors. Thus, this study illustrates the current trends, hotspots, and emerging frontiers and provides new insight and guidance for searching for new diagnostic biomarkers and clinical trials for glaucoma in the future. Furthermore, international collaborations can also be used to broaden and deepen the field of microRNAs in glaucoma research.
青光眼类似于神经退行性疾病，导致全球不可逆转的视力丧失。尽管进行了广泛的研究，但青光眼的病理生理机制仍不清楚，也尚未确定针对青光眼的完整治疗方法。最近的研究表明，microRNAs 可以作为青光眼的诊断生物标志物或治疗靶点；然而，针对 microRNAs 在青光眼研究中的应用，很少有文献计量学研究关注这一领域。在这里，我们采用文献计量学分析方法对青光眼研究中的 microRNAs 领域进行了研究，以展示当前的趋势和研究热点，并呈现该领域过去和新兴趋势的可视化图谱。在这项研究中，我们从 Web of Science 数据库中检索了 2007 年至 2022 年期间以该领域为中心的出版物。然后，我们使用 VOSviewer、CiteSpace、Scimago Graphica 和 Microsoft Excel 来展示共现分析、共被引分析、趋势、热点以及作者、机构、期刊和国家/地区的贡献的可视化表示。美国是主要贡献者。 在这个领域发表的文章最多。在过去的 15 年中，各个国家、组织和作者在该领域的出版物和引文数量呈指数级增长。因此，本研究说明了当前的趋势、热点和新兴前沿，并为未来寻找青光眼的新诊断生物标志物和临床试验提供了新的见解和指导。此外，还可以利用国际合作来拓宽和深化青光眼研究中的 microRNAs 领域。
