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柠檬酸盐在草酸钙尿路结石治疗和预防中的重要性。

The importance of citrates in treatment and prophylaxis of calcium oxalate urinary stones.

作者信息

Barbera Michele, Tsirgiotis Andreas, Barbera Mauro, Paola Quintino

机构信息

Operative Unit of Urology, Ospedale Giovanni Paolo II, Sciacca.

出版信息

Arch Ital Urol Androl. 2016 Dec 30;88(4):343-344. doi: 10.4081/aiua.2016.4.343.

DOI:10.4081/aiua.2016.4.343
PMID:28073210
Abstract

About 10% of the people is the subject of an episode of kidney stones during their lifetime, about 70% of these people undergoes relapses. About 80% of the urinary stones contains calcium, of wich 80% is formed of calcium oxalate, in pure form or associated with calcium phosphate. Therefore we can saythat in most cases (about 65%) the urinary stones are composedof calcium oxalate. Use of supplements of potassium citrate and magnesium citrate can help in the prevention of kidney stones of calcium oxalate, but mostly they can be used in the days before a shockwaves lithotripsy treatment to make the stones more fragile to the effect of the shock waves. A case of successful treatment with magnesium potassium citrate of a SWL resistant ureteral stone is presented.

摘要

约10%的人在一生中会经历一次肾结石发作,其中约70%的人会复发。约80%的尿路结石含有钙,其中80%由草酸钙形成,呈纯形式或与磷酸钙结合。因此可以说,在大多数情况下(约65%),尿路结石由草酸钙组成。使用柠檬酸钾和柠檬酸镁补充剂有助于预防草酸钙肾结石,但主要可在冲击波碎石治疗前几天使用,以使结石对冲击波的作用更脆弱。本文介绍了一例使用柠檬酸镁钾成功治疗对冲击波碎石术耐药的输尿管结石的病例。

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Arch Ital Urol Androl. 2016 Dec 30;88(4):343-344. doi: 10.4081/aiua.2016.4.343.
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