胰腺淋巴瘤并发早期慢性丙型肝炎
Pancreatic lymphoma complicating early stage chronic hepatitis C.
作者信息
Bhagat Vicky H, Sepe Thomas
机构信息
Gastroenterology Department of Women & Infants Hospital, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA.
Brown University Warren Alpert Medical School, Providence, Rhode Island, USA.
出版信息
BMJ Case Rep. 2017 Jan 10;2017:bcr2016216698. doi: 10.1136/bcr-2016-216698.
Hepatitis C virus (HCV) infection has also been associated with many extrahepatic manifestations including the development of B-cell non-Hodgkin's lymphoma (NHL). Primary pancreatic lymphoma is very rare and comprises 2.2% of NHL and 4.9% of all pancreatic malignancies. Our patient was a woman with a history of infection with HCV found to have a mass in the head of the pancreas. Biopsy of the mass revealed a high-grade B-cell lymphoma consistent with Burkitt's lymphoma. Our case reflects a need to initiate antiviral therapy for all patients infected with HCV even in early stages of fibrosis to prevent cirrhosis and other extrahepatic manifestations of infection with HCV.
丙型肝炎病毒（HCV）感染还与许多肝外表现有关，包括B细胞非霍奇金淋巴瘤（NHL）的发生。原发性胰腺淋巴瘤非常罕见，占NHL的2.2%，占所有胰腺恶性肿瘤的4.9%。我们的患者是一名有HCV感染史的女性，发现胰腺头部有一个肿块。肿块活检显示为高级别B细胞淋巴瘤，符合伯基特淋巴瘤。我们的病例表明，即使在纤维化早期，也需要对所有HCV感染患者启动抗病毒治疗，以预防肝硬化和HCV感染的其他肝外表现。
Zotero 插件