Stefani D V, Semyonov A V, Kudrina G P
Moscow Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of the Russian Soviet Federated Socialist Republic.
Immunol Lett. 1989 Sep;22(3):193-4. doi: 10.1016/0165-2478(89)90189-2.
Twenty-three guinea pigs, presensitized with horse serum, were injected intracardially with 1 ml of 1.5 X 10(-4) M cytochalasin B in a 2.5% dimethyl sulfoxide solution, 1.5 h before being challenged with the serum. Eighteen of the guinea pigs (80%) survived. A single intracardiac injection of cytochalasin B to the control group of guinea pigs at 1.5 h before administration of the allergen did not prevent their sensitization and death following challenge.
23只预先用马血清致敏的豚鼠，在接受血清攻击前1.5小时，经心内注射1毫升含1.5×10(-4)M细胞松弛素B的2.5%二甲基亚砜溶液。18只豚鼠（80%）存活。在给予变应原前1.5小时，对豚鼠对照组进行单次心内注射细胞松弛素B，不能防止其在攻击后致敏和死亡。
