来自自体IgG的Fc片段抗体对豚鼠过敏反应的抑制作用。
Inhibition of anaphylactic reaction in guinea pigs by antibodies to fragments of Fc from autologous IgG.
作者信息
Matre R, Grov A
出版信息
Int Arch Allergy Appl Immunol. 1976;52(1-4):422-4. doi: 10.1159/000231711.
PMID:828151
Abstract
The effect of antibodies to Fc subfragments of guinea pig IgG on the anaphylactic reaction in guinea pigs has been studied. Control animals were immunized with guinea pig IgG and Fab, human IgG and albumin. All animals with antibodies to fragments of autologous Fc survived challenge with horse serum, whereas the control animals died in anaphylactic shock.
摘要
已经研究了针对豚鼠IgG的Fc亚片段的抗体对豚鼠过敏反应的影响。对照动物用豚鼠IgG和Fab、人IgG和白蛋白进行免疫。所有具有针对自身Fc片段抗体的动物在接受马血清攻击后存活下来，而对照动物死于过敏性休克。
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