Pérez-Segura P, Palacio J E, Vázquez L, Monereo S, de Las Peñas R, de Icaya P Martínez, Grávalos C, Lecube A, Blasco A, García-Almeida J M, Barneto I, Goday A
Servicio de Oncología Médica, Hospital Clínico Universitario San Carlos, Calle Profesor Martín Lagos, s/n, 28040, Madrid, Spain.
Servicio de Endocrinología, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Tenerife, Spain.
Clin Transl Oncol. 2017 Jun;19(6):682-694. doi: 10.1007/s12094-016-1601-2. Epub 2017 Jan 10.
The relationship between obesity and cancer is clear and is present at all times during course of the disease. The importance of obesity in increasing the risk of developing cancer is well known, and some of the most prevalent tumours (breast, colorectal, and prostate) are directly related to this risk increase. However, there is less information available on the role that obesity plays when the patient has already been diagnosed with cancer. Certain data demonstrate that in some types of cancer, obese patients tolerate the treatments more poorly. Obesity is also known to have an impact on the prognosis, favouring lower survival rates or the appearance of secondary tumours. In this consensus statement, we will analyse the scientific evidence on the role that obesity plays in patients already diagnosed with cancer, and the available data on how obesity control can improve the quality of daily life for the cancer patient.
肥胖与癌症之间的关系是明确的,且在疾病过程中的任何时候都存在。肥胖在增加患癌风险方面的重要性是众所周知的,一些最常见的肿瘤(乳腺癌、结直肠癌和前列腺癌)都与这种风险增加直接相关。然而,关于肥胖在患者已被诊断患有癌症时所起的作用,相关信息较少。某些数据表明,在某些类型的癌症中,肥胖患者对治疗的耐受性更差。肥胖还已知会对预后产生影响,导致生存率降低或出现继发性肿瘤。在本共识声明中,我们将分析关于肥胖在已确诊癌症患者中所起作用的科学证据,以及关于控制肥胖如何能改善癌症患者日常生活质量的现有数据。