Sarda A K, Rohtagi M, Shukla N K, Bal S, Sharma A, Kapur M M
Indian J Pediatr. 1989 May-Jun;56(3):379-83. doi: 10.1007/BF02722305.
Eleven cases of thyroid cancer occurring in patients below 15 years of age are presented. The youngest patient was 4 years old. There were 4 boys and 7 girls in the study group. None of the patients had received head and neck irradiation. All patients had well differentiated cancers; there were 4 follicular carcinomas and 3 of these occurred in patients below 10 years of age. Six patients presented with solitary thyroid nodules. Lymph node involvement had occurred in 63.7% of cases. One patient presented with CNS metastasis. Treatment aimed at near total thyroidectomy was performed in 9 patients. Two patients died of the disease during the follow up period and another 3 patients are alive. Postoperatively radioactive iodine was routinely used for evaluating and treating residual and recurrent disease.
本文报告了11例15岁以下儿童甲状腺癌患者。最年幼的患者为4岁。研究组中有4名男孩和7名女孩。所有患者均未接受过头颈部放疗。所有患者均为高分化癌；其中有4例滤泡状癌，3例发生在10岁以下患者中。6例患者表现为甲状腺单发结节。63.7%的病例出现淋巴结受累。1例患者出现中枢神经系统转移。9例患者接受了近全甲状腺切除术。2例患者在随访期间死于该疾病，另外3例患者存活。术后常规使用放射性碘评估和治疗残留及复发性疾病。
