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医生对与护理机构药物不良事件干预相关的临床药师服务的看法。

Physician Perceptions of Consultant Pharmacist Services Associated with an Intervention for Adverse Drug Events in the Nursing Facility.

作者信息

Kane-Gill Sandra L, Hanlon Joseph T, Fine Michael J, Perera Subashan, Culley Colleen M, Studenski Stephanie A, Nace Dave A, Boyce Richard D, Castle Nicholas G, Handler Steven M

出版信息

Consult Pharm. 2016 Dec 1;31(12):708-720. doi: 10.4140/TCP.n.2016.708.

Abstract

OBJECTIVE

To assess the importance and performance of consultant pharmacist services delivered before and after an intervention to detect and manage adverse drug events among nursing facility residents.

DESIGN

Before and after intervention survey of physicians participating in a randomized, controlled trial.

SETTING

Four nonprofit, academically affiliated nursing facilities.

PARTICIPANTS

Attending physicians providing nursing facility care who were randomized to intervention or control groups.

INTERVENTIONS

Within the intervention arm, consultant pharmacists provided academic detailing in which trained health care professionals visit practicing physicians in their offices and present the most up-to-date clinical information. Physicians responded to alerts from a medication monitoring system, adjudicated system alerts for adverse drug events (ADEs), and provided structured recommendations about ADE management.

MAIN OUTCOME MEASURES

We compared physicians' assessments of the importance and performance of consultant pharmacist services before and after the trial intervention in the intervention and control groups.

RESULTS

In the intervention group, ratings of importance increased for all 24 survey questions, and 5 of the changes were statistically significant (P < 0.05). In the control group, ratings of importance increased for 16 questions, and none of the changes were statistically significant. In the intervention group, ratings of performance increased for all 24 questions, and 20 of the changes were statistically significant. In the control group, ratings of performance increased for 16 questions, and none of the changes was statistically significant.

CONCLUSION

A multifaceted, consultant pharmacist-led intervention comprising academic detailing, computerized decision support, and structured communication framework can improve physicians' assessment of importance and performance of consultant pharmacist services.

ABBREVIATIONS

ADE = Adverse drug event, M = Statistically significant mean, RCT = Randomized controlled trial, SBAR = Situation, Background, Discussion, Recommendation, SD = Standard deviation.

摘要

目的

评估在一项旨在检测和管理疗养院居民药物不良事件的干预措施前后,临床药师服务的重要性及效果。

设计

对参与一项随机对照试验的医生进行干预前后的调查。

地点

四家非营利性、与学术机构相关的疗养院。

参与者

为疗养院居民提供护理服务的主治医生,他们被随机分配到干预组或对照组。

干预措施

在干预组中,临床药师提供学术指导,即由经过培训的医疗保健专业人员到执业医生的办公室拜访,并提供最新的临床信息。医生对药物监测系统发出的警报做出反应,对药物不良事件(ADEs)的系统警报进行判定,并提供关于ADEs管理的结构化建议。

主要观察指标

我们比较了干预组和对照组在试验干预前后医生对临床药师服务的重要性及效果的评估。

结果

在干预组中,24个调查问题的重要性评分均有所提高,其中5项变化具有统计学意义(P < 0.05)。在对照组中,16个问题的重要性评分有所提高,但没有一项变化具有统计学意义。在干预组中,24个问题的效果评分均有所提高,其中20项变化具有统计学意义。在对照组中,16个问题的效果评分有所提高,但没有一项变化具有统计学意义。

结论

由临床药师主导的多方面干预措施,包括学术指导、计算机化决策支持和结构化沟通框架,可以提高医生对临床药师服务的重要性及效果的评估。

缩写

ADE = 药物不良事件,M = 具有统计学意义的均值,RCT = 随机对照试验,SBAR = 情况、背景、讨论、建议,SD = 标准差

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