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一种用于检测皮肤癌的临床辅助工具:分诊综合皮肤镜算法(TADA)。

A Clinical Aid for Detecting Skin Cancer: The Triage Amalgamated Dermoscopic Algorithm (TADA).

作者信息

Rogers T, Marino M L, Dusza S W, Bajaj S, Usatine R P, Marchetti M A, Marghoob A A

机构信息

From the Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY (TR, MLM, SWD, SB, MAM, AAM); Department of Family and Community Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX (RPU).

出版信息

J Am Board Fam Med. 2016 Nov 12;29(6):694-701. doi: 10.3122/jabfm.2016.06.160079.

Abstract

PURPOSE

Family physicians (FPs) frequently evaluate skin lesions but may not have the necessary training to accurately and confidently identify lesions that require skin biopsy or specialist referral. We evaluated the diagnostic performance of a new, simplified dermoscopy algorithm for skin cancer detection.

METHODS

In this cross-sectional, observation study, attendees of a dermoscopy course evaluated 50 polarized dermoscopy images of skin lesions (27 malignant and 23 benign) using the Triage Amalgamated Dermoscopic Algorithm (TADA). The dermoscopic criteria of TADA include architectural disorder (ie, disorganized or asymmetric distribution of colors and/or structures), starburst pattern, blue-black or gray color, white structures, negative network, ulcer, and vessels. The study occurred after 1 day of basic dermoscopy training. Clinical information related to palpation (ie, firm, dimpling) was provided when relevant.

RESULTS

Of 200 course attendees, 120 (60%) participated in the study. Participants included 64 (53.3%) dermatologists and 41 (34.2%) primary care physicians, 19 (46.3%) of whom were FPs. Fifty-two (43%) individuals had no previous dermoscopy training. Overall, the sensitivity and specificity of TADA for malignant skin lesions was 94.8% and 72.3%, respectively. Previous dermoscopy training and years of dermoscopy experience were not associated with diagnostic sensitivity (P = .13 and P = .05, respectively) or specificity (P = .36 and P = .21, respectively). Specialty type was not associated with sensitivity (P = .37) but dermatologists had a higher specificity than nondermatologists (79% v. 72%, P = .008).

CONCLUSIONS

After basic instruction, TADA may be a useful dermoscopy algorithm for FPs who examine skin lesions as it has a high sensitivity for detecting skin cancer.

摘要

目的

家庭医生(FPs)经常对皮肤病变进行评估,但可能没有必要的培训来准确且自信地识别需要进行皮肤活检或转诊至专科医生的病变。我们评估了一种用于皮肤癌检测的新的简化皮肤镜算法的诊断性能。

方法

在这项横断面观察研究中,参加皮肤镜课程的人员使用分类合并皮肤镜算法(TADA)对50张皮肤病变的偏振皮肤镜图像(27例恶性和23例良性)进行评估。TADA的皮肤镜标准包括结构紊乱(即颜色和/或结构的无序或不对称分布)、星芒状模式、蓝黑色或灰色、白色结构、阴性网络、溃疡和血管。该研究在进行1天的基础皮肤镜培训后开展。相关时会提供与触诊有关的临床信息(即质地硬、酒窝征)。

结果

在200名课程参与者中,120名(60%)参与了研究。参与者包括64名(53.3%)皮肤科医生和41名(34.2%)初级保健医生,其中19名(46.3%)是家庭医生。52名(43%)个体此前没有皮肤镜培训经历。总体而言,TADA对恶性皮肤病变的敏感性和特异性分别为94.8%和72.3%。既往皮肤镜培训和皮肤镜经验年限与诊断敏感性(分别为P = 0.13和P = 0.05)或特异性(分别为P = 0.36和P = 0.21)均无关。专业类型与敏感性无关(P = 0.37),但皮肤科医生的特异性高于非皮肤科医生(79%对72%,P = 0.008)。

结论

经过基础指导后,TADA对于检查皮肤病变的家庭医生而言可能是一种有用的皮肤镜算法,因为它对检测皮肤癌具有较高的敏感性。

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