Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
Cell Metab. 2017 Jan 10;25(1):4-5. doi: 10.1016/j.cmet.2016.12.019.
Understanding the mammalian respiratory complex I assembly has been an arduous task due to the lack of appropriate techniques and the complexity of the process. In this issue, a new tour de force based on complexome profiling provides an encyclopedic description of the process (Guerrero-Castillo et al., 2017).
由于缺乏适当的技术和过程的复杂性,理解哺乳动物呼吸复合物 I 的组装一直是一项艰巨的任务。在本期杂志中,一项基于复合物组学分析的新力作提供了对这一过程的百科全书式描述(Guerrero-Castillo 等人,2017 年)。