Thom T J
Division of Epidemiology and Clinical Applications, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892.
Int J Epidemiol. 1989;18(3 Suppl 1):S20-8.
Mortality trends are described for heart disease, its main subgroup coronary heart disease (CHD), and total mortality for men and women 45-64 years of age from 1950 to 1985 in 27 countries. In contrast to the epidemic rise in mortality from CHD prior to the 1960s, the death rate is declining in most industrialized countries except in Eastern Europe where trends remain upward. Mortality from CHD was upwards in 18 countries in the 1970s and in only four countries in the 1980s. Peaks for CHD occurred earlier in women than men. With some exceptions, declines were greater for higher than lower rate countries. In many countries, CHD declines are accompanied by a corresponding downward change in total mortality, which suggests that the declines are real. Although in several countries there is substantial mortality from heart diseases other than CHD, generally there is good correspondence in trends between them over the 35-year period. There is also a trend toward less intercountry variability in death rates and proportionate mortality for CHD. But the North-South high-to-low gradient in Europe continues in 1985, and there remains at least a fourfold difference for men and an eightfold difference for women between the highest and lowest CHD rates. The male/female ratios of the rates, while narrowing in many countries, vary from 3:1 to 6:1 among the 27 countries.
本文描述了1950年至1985年期间27个国家45至64岁男性和女性的心脏病、其主要亚组冠心病(CHD)的死亡率趋势以及总死亡率。与20世纪60年代之前冠心病死亡率的流行上升形成对比的是,除东欧国家死亡率趋势仍在上升外,大多数工业化国家的死亡率正在下降。20世纪70年代,18个国家的冠心病死亡率呈上升趋势,而到了80年代,只有4个国家如此。冠心病死亡率的峰值在女性中出现得比男性早。除了一些例外情况,死亡率较高的国家比死亡率较低的国家下降幅度更大。在许多国家,冠心病死亡率的下降伴随着总死亡率相应的下降,这表明这种下降是真实的。尽管在几个国家,除冠心病外的其他心脏病导致的死亡率很高,但总体而言,在这35年期间,它们之间的趋势有很好的对应关系。冠心病死亡率和比例死亡率的国家间差异也有减小的趋势。但是欧洲1985年南北之间的高到低梯度仍然存在,冠心病死亡率最高和最低的国家之间,男性至少有四倍的差异,女性至少有八倍的差异。在这27个国家中,冠心病死亡率的男女比例虽然在许多国家有所缩小,但仍在3:1至6:1之间。