D'Agostino R B, Kannel W B, Belanger A J, Sytkowski P A
Mathematics Department, Boston University, MA 02215.
Int J Epidemiol. 1989;18(3 Suppl 1):S67-72.
In a preliminary analysis to assess secular changes in cardiac morbidity, mortality, and risk factors in the Framingham Heart Study, there is a suggestion of decline in coronary heart disease (CHD) mortality in women but not in men. For subjects age 55 to 64 in 1953, 1963 and 1973, the ten-year CHD mortality rates per 1000 were 93, 84 and 99 for men; and 34, 39, and 24 for women, respectively. In contrast, CHD prevalence rates have increased significantly for men (102, 134 and 159 per 1000) and marginally for women (55, 65 and 69 per 1000). Incidence of CHD increased slightly in men (187, 210 and 208 per 1000 over the three decades) and decreased in women (131, 132, 110). Some coronary risk factors improved, while others changed unfavourably.
在一项评估弗雷明汉心脏研究中心脏病发病率、死亡率及危险因素长期变化的初步分析中,有迹象表明女性冠心病(CHD)死亡率呈下降趋势,而男性则不然。对于1953年、1963年和1973年年龄在55至64岁的受试者,每1000人中男性的十年冠心病死亡率分别为93、84和99;女性分别为34、39和24。相比之下,男性的冠心病患病率显著上升(每1000人分别为102、134和159),女性略有上升(每1000人分别为55、65和69)。男性冠心病发病率略有上升(三十年间每1000人分别为187、210和208),女性则有所下降(131、132、110)。一些冠心病危险因素有所改善,而另一些则朝着不利方向变化。