Mondiello Taryn B, Stutzman Lauren A
Consult Pharm. 2017 Jan 1;32(1):47-62. doi: 10.4140/TCP.n.2017.54.
To assess pharmacists' impact on optimizing pharmacotherapy among geriatric patients.
Single-site, prospective, quality-improvement project.
Primary care at a Veterans Affairs medical center.
Thirteen males 75 years of age and older were included.
Recommendations were made by pharmacists to optimize prescribing.
Differences between specific instances of suboptimal prescribing before and after pharmacists' recommendations, the percentage of pharmacists' recommendations accepted, and the top most commonly prescribed psychotropic medications and their most common indications.
Sixty-three recommendations were made by pharmacists, and 48% of these recommendations were accepted by providers. There was a 27% reduction of the use of high-risk medications, a 44% reduction of omissions of care, and a 74% reduction of incomplete medication monitoring after pharmacists' recommendations. The most commonly prescribed psychotropic medications were zolpidem (31%), lorazepam (23%), and clonazepam and temazepam (each 15%). The most common indications for these medications were anxiety and insomnia (each 46%), with 8% of patients having an indication for both.
Pharmacists' recommendations improved geriatric pharmacotherapy by decreasing the overall instances of suboptimal prescribing.
评估药剂师对优化老年患者药物治疗的影响。
单中心、前瞻性质量改进项目。
一家退伍军人事务医疗中心的初级保健机构。
纳入了13名75岁及以上的男性。
药剂师提出优化处方的建议。
药剂师提出建议前后次优处方具体实例的差异、药剂师建议被采纳的百分比、最常开具的精神药物及其最常见适应证。
药剂师提出了63条建议,其中48%被医疗服务提供者采纳。在药剂师提出建议后,高风险药物的使用减少了27%,护理遗漏减少了44%,用药监测不完整的情况减少了74%。最常开具的精神药物是唑吡坦(31%)、劳拉西泮(23%)、氯硝西泮和替马西泮(各15%)。这些药物最常见的适应证是焦虑和失眠(各46%),8%的患者同时有这两种适应证。
药剂师的建议通过减少次优处方的总体实例,改善了老年患者的药物治疗。