Pyszka Lauren L, Seys Ranola Trisha M, Milhans Sara M
William S. Middleton Veterans Affairs (VA) Hospital, Madison, Wisconsin 53705, USA.
Consult Pharm. 2010 Jun;25(6):365-73. doi: 10.4140/TCP.n.2010.365.
Pharmacists' interventions of potentially inappropriate medications (PIM) decrease hospital admissions and emergency department visits and provide health-cost savings. The newest criterion to address PIMs is STOPP/START (Screening Tool of Older Person's Prescriptions/Screening Tool to Alert Doctor's to the Right Treatment). The purpose of this study is to determine the frequency of PIMs in a geriatric population.
DESIGN/SETTING/PARTICIPANTS: A retrospective chart review of 511 patients was conducted at a Veterans Affairs hospital in patients > 70 years of age.
Charts were reviewed at hospital admission, discharge, and first follow-up clinic visit post-discharge for incidence of STOPP/START medications.
MAIN OUTCOME MEASURE(S): STOPP/START criterion was applied to patients' medication lists and documented with omission or commission medications.
One hundred eleven (22%) patients met inclusion criteria. STOPP/START medication use was similar at all time points. Medications without an appropriate diagnosis were the most common type of STOPP criteria identified. Aspirin (> 150 mg daily) had high frequency of use. Incidence of START was highest with omissions of statin therapy, angiotensin-converting enzyme (ACE) inhibitor with heart failure, and vitamin D in patients with osteoporosis.
The results demonstrated that inappropriate prescribing and omission of medications occurs consistently at all points of care. STOPP/START criteria are more comprehensive than previous inappropriate prescribing lists. Utilization of a clinical pharmacist would benefit patients through elimination of PIMs and identification of medications to optimize patient care.
药剂师对潜在不适当用药(PIM)的干预可减少住院次数和急诊就诊次数,并节省医疗成本。解决PIM的最新标准是STOPP/START(老年人处方筛查工具/提醒医生正确治疗的筛查工具)。本研究的目的是确定老年人群中PIM的发生频率。
设计/地点/参与者:在一家退伍军人事务医院对511名70岁以上患者进行了回顾性病历审查。
在患者入院、出院时以及出院后的首次随访门诊就诊时审查病历,以确定STOPP/START药物的发生率。
将STOPP/START标准应用于患者的用药清单,并记录漏用或误用的药物。
111名(22%)患者符合纳入标准。在所有时间点,STOPP/START药物的使用情况相似。没有适当诊断的药物是最常见的被确定的STOPP标准类型。阿司匹林(每日>150毫克)的使用频率较高。START的发生率在漏用他汀类药物治疗、心力衰竭患者漏用血管紧张素转换酶(ACE)抑制剂以及骨质疏松症患者漏用维生素D时最高。
结果表明,在所有护理环节中,不适当的处方和药物漏用情况持续存在。STOPP/START标准比以前的不适当处方清单更全面。临床药师的参与将通过消除PIM和识别优化患者护理的药物而使患者受益。