Damianov C, Patrashkov T, Tonchev T, Engibarov A, Kasabov V, Chouchkova M
Department of Immunology, Research Institute of Infectious and Parasitic Disease, Sofia, Bulgaria.
Int Urol Nephrol. 1989;21(3):305-12. doi: 10.1007/BF02559741.
A total of 42 patients were involved in the study of the effectiveness of BCG vaccine on superficial bladder tumours. The new Bulgarian vaccine CALGEVAX was administered intravesically in consecutive instillations once weekly and then once monthly for a period of 11 months. For intradermal application the F-70 subcellular preparation was used. On the grounds of their initial experience in the treatment of superficial bladder tumours with unspecific immunotherapy the authors would like to express their confidence in the effectiveness of the intravesical application of BCG vaccine.
共有42名患者参与了卡介苗对浅表性膀胱肿瘤疗效的研究。新型保加利亚疫苗CALGEVAX通过膀胱内连续灌注给药,每周一次,然后每月一次,共11个月。皮内应用则使用F - 70亚细胞制剂。基于他们最初用非特异性免疫疗法治疗浅表性膀胱肿瘤的经验,作者们对膀胱内应用卡介苗疫苗的有效性表示有信心。