Sugahara T, Yanagihara Y, Uyama C, Maeda H, Takafuchi M, Azumi T
Department of Radiology, National Cardiovascular Center Research Institute, Osaka, Japan.
Invest Radiol. 1989 Sep;24(9):672-7. doi: 10.1097/00004424-198909000-00005.
We developed a new, cineangiographic method to accurately measure the dynamic changes in the internal diameter of human arteries in vivo. Cine films were digitized at a spatial resolution of 4 microns/pixel, using a line image sensor. The vessel edges, with a Gaussian fit to a unilateral profile curve of the vessel, were determined with the aid of a computer program. We measured contrast-filled cylinder vessel models (2 to 7 mm in diameter) and evaluated precision, accuracy and linearity of the diameter measurement. A pulsatile vessel model of about 3.9 mm in internal diameter was used to examine the reliability of our method for detecting arterial wall motion. If the coefficient of variation of the vessel diameter determined cineangiographically was less than 2.2% we considered the cineangiograms sufficiently accurate to determine the internal vessel diameter and evaluate arterial distensibility.
我们开发了一种新的电影血管造影方法，用于在体内准确测量人体动脉内径的动态变化。使用线图像传感器，以4微米/像素的空间分辨率对电影胶片进行数字化处理。借助计算机程序，通过对血管单侧轮廓曲线进行高斯拟合来确定血管边缘。我们测量了造影剂填充的圆柱血管模型（直径2至7毫米），并评估了直径测量的精度、准确性和线性度。使用内径约为3.9毫米的脉动血管模型来检验我们检测动脉壁运动方法的可靠性。如果通过电影血管造影确定的血管直径变异系数小于2.2%，我们认为电影血管造影足够准确，能够确定血管内径并评估动脉扩张性。
