Sandor T, Spears J R
Comput Biomed Res. 1985 Dec;18(6):531-43. doi: 10.1016/0010-4809(85)90028-x.
Problems related to the precision of computerized measurement and analysis of blood vessel diameter from digitized cineangiographic vessel images are described, and shortcomings of the conventional definition of percent stenosis are discussed. Formulae for the precision of percent stenosis, for the minimum significant measurable changes in blood vessel diameter, for the necessary scanning resolution, and for absolute vessel diameter measurement are provided. A Monte Carlo procedure-based technique for assessing the effect of radiographic noise on the location of vessel boundaries within the transverse densitometric image profile is presented and applied to contrast-filled cylindrical phantoms. The results demonstrate the feasibility for achieving subpixel resolution in computerized detection of vessel edges and diameter measurement.
描述了与从数字化血管造影血管图像进行计算机化测量和分析血管直径的精度相关的问题，并讨论了传统狭窄百分比定义的缺点。提供了狭窄百分比精度、血管直径最小可测量显著变化、必要扫描分辨率以及绝对血管直径测量的公式。提出了一种基于蒙特卡罗程序的技术，用于评估射线照相噪声对横向密度图像轮廓内血管边界位置的影响，并将其应用于造影剂填充的圆柱形体模。结果证明了在计算机化检测血管边缘和直径测量中实现亚像素分辨率的可行性。
