Hawass N E, al-Badawi M G, Fatani J A, Meshari A A, Edrees Y B, Jabbar F A
Department of Radiology, King Khalid University Hospital, Riyadh, Saudi Arabia.
Invest Radiol. 1989 Sep;24(9):711-20. doi: 10.1097/00004424-198909000-00012.
The authors describe a new technique "necrogram" for post-mortem fetal investigations that uses ionic contrast media and employs the principles of diffusion and osmosis for clearing the fetus from contrast injection. It was possible to perform subsequent contrast examinations without the problem of overlapping structures. The study was conducted on 1,500 fetuses with more than 12,000 contrast examinations performed, followed by autopsy. In a sample of 250 fetuses undergoing 2,135 contrast examinations, similar results were obtained from necrogram and autopsy in 79% of the fetuses examined. Details are given of the 21% of the studies in which discrepancies were noted between necrogram and autopsy. The result showed that necrogram was comparable to autopsy and that luminal anatomy can be best visualized by necrogram, a laborious and almost impossible task in autopsy. It was apparent that post-mortem diagnostic precision can only be obtained by employing both necrogram and autopsy, one for visualization of the inner and the other for the outer appearance of the organs.
作者描述了一种用于死胎检查的新技术“坏死造影术”，该技术使用离子型造影剂，并运用扩散和渗透原理将造影剂注入胎儿体内以进行清理。这样就可以进行后续的造影检查，而不会出现结构重叠的问题。该研究对1500例胎儿进行了超过12000次造影检查，随后进行了尸检。在250例接受2135次造影检查的胎儿样本中，79%接受检查的胎儿在坏死造影术和尸检中得到了相似的结果。文中给出了21%的研究细节，这些研究在坏死造影术和尸检之间发现了差异。结果表明，坏死造影术与尸检相当，并且通过坏死造影术可以最好地观察管腔解剖结构，而这在尸检中是一项费力且几乎不可能完成的任务。显然，只有同时采用坏死造影术和尸检，一个用于观察器官内部，另一个用于观察器官外观，才能获得死后诊断的精确性。
