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经鼻气管插管期间的鼻出血:一项关于带有后倾斜面的派克Flex-Tip™经鼻气管内导管与标准经鼻RAE气管内导管的随机试验。

Epistaxis during nasotracheal intubation: a randomized trial of the Parker Flex-Tip™ nasal endotracheal tube with a posterior facing bevel versus a standard nasal RAE endotracheal tube.

作者信息

Earle Rosie, Shanahan Enda, Vaghadia Himat, Sawka Andrew, Tang Raymond

机构信息

Department of Anaesthesia, Vancouver Coastal Health, Suite JPP2449, 855 West 12th Avenue, Vancouver, BC, V5Z 1M9, Canada.

出版信息

Can J Anaesth. 2017 Apr;64(4):370-375. doi: 10.1007/s12630-017-0813-4. Epub 2017 Jan 11.

Abstract

PURPOSE

Nasotracheal intubation is a widely performed technique to facilitate anesthesia induction during oral, dental, and maxillofacial surgeries. The technique poses several risks not encountered with oropharyngeal intubation, most commonly epistaxis due to nasal mucosal abrasion. The purpose of this study was to test whether the use of the Parker Flex-Tip™ (PFT) nasal endotracheal tube (ETT) with a posterior facing bevel reduces epistaxis when compared with the standard nasal RAE ETT with a leftward facing bevel.

METHODS

Sixty American Society of Anesthesiologists physical status I and II patients undergoing oral or maxillofacial surgery with nasotracheal intubation were recruited. Patients were randomized to either a standard nasal RAE ETT or a PFT nasal ETT. The ETT was thermosoftened and lubricated for both study groups prior to insertion, and the size of the tube was chosen at the discretion of the attending anesthesiologist. The primary outcome was the incidence of epistaxis, with a secondary outcome of epistaxis severity (scored as none, mild, moderate, or severe). An investigator measured both outcomes five minutes after intubation was completed.

RESULTS

Mild or moderate epistaxis was experienced by 22 of 30 (73%) patients in the PFT group compared with 21 of 30 (70%) patients in the standard nasal RAE ETT group (absolute risk reduction, 3%; 95% confidence interval, -19 to 25; P = 0.78). There were no occurrences of severe epistaxis in either group.

CONCLUSION

There was no difference in the incidence or severity of epistaxis following nasal intubation using the Parker Flex-Tip nasal ETT when compared with a standard nasal RAE ETT. This trial was registered at ClinicalTrials.gov, identifier: NCT02315677.

摘要

目的

鼻气管插管是一种广泛应用于口腔、牙科和颌面外科手术中辅助麻醉诱导的技术。该技术存在一些口咽插管未出现的风险,最常见的是因鼻黏膜擦伤导致鼻出血。本研究的目的是测试与标准的向左开口斜面的鼻腔RAE气管内导管(ETT)相比,使用后开口斜面的派克Flex-Tip™(PFT)鼻气管内导管是否能减少鼻出血的发生。

方法

招募60例接受鼻气管插管的美国麻醉医师协会身体状况I级和II级的口腔或颌面外科手术患者。患者被随机分为标准鼻腔RAE ETT组或PFT鼻ETT组。两组在插入前均对ETT进行热软化和润滑处理,导管尺寸由主治麻醉医师酌情选择。主要结局是鼻出血的发生率,次要结局是鼻出血的严重程度(分为无、轻度、中度或重度)。一名研究者在插管完成5分钟后测量这两个结局。

结果

PFT组30例患者中有22例(73%)出现轻度或中度鼻出血,而标准鼻腔RAE ETT组30例患者中有21例(70%)出现轻度或中度鼻出血(绝对风险降低3%;95%置信区间,-19至25;P = 0.78)。两组均未出现严重鼻出血。

结论

与标准鼻腔RAE ETT相比,使用派克Flex-Tip鼻ETT进行鼻插管后鼻出血的发生率和严重程度没有差异。本试验已在ClinicalTrials.gov注册,标识符:NCT02315677。

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