Ammari B, Biltz H, Hotze A, Küster W, Grünwald F, Biersack H J, Kreysel H W
Institut für klinische und experimentelle Nuklearmedizin, Bonn.
Hautarzt. 1989 Sep;40(9):559-63.
The frequency and extent of heart involvement in progressive systemic scleroderma (PSS) can be underestimated when current clinical diagnostic methods are used. We therefore studied 53 PSS patients with planar (201Tl) chloride myocardial scintigraphy, and 44 PSS patients with radionuclide ventriculography using red blood cells labeled in vitro with 99mTc. Comparison of maximal exercise and resting myocardial scans demonstrated pathologic findings in 18 of 38 patients. In 10% of the patients abnormal ejection fraction values (less than 50%) and Fourier analysis were found on radionuclide ventriculography. Myocardial scintigraphy in conjunction with other diagnostic modalities thus provides useful information for the evaluation of heart involvement in PSS.
当采用目前的临床诊断方法时，进行性系统性硬化症（PSS）中心脏受累的频率和程度可能会被低估。因此，我们对53例PSS患者进行了平面（201Tl）氯化物心肌闪烁扫描，并对44例PSS患者使用体外标记有99mTc的红细胞进行放射性核素心室造影。对最大运动量和静息心肌扫描的比较显示，38例患者中有18例存在病理结果。在10%的患者中，放射性核素心室造影发现射血分数值异常（小于50%）并进行了傅里叶分析。心肌闪烁扫描结合其他诊断方法可为评估PSS中的心脏受累提供有用信息。
