Ammari B, Hotze A, Biltz H, Grünwald F, Küster W, Biersack H J, Kreysel H W
Institut für klinische und experimentelle Nuklearmedizin Bonn.
Hautarzt. 1991 Oct;42(10):627-30.
Kidney involvement is one of the most frequent causes of death in progressive systemic scleroderma (PSS). It is therefore important to detect potential impairment of renal function in PSS very early. In 76 patients referred for nuclear medicine diagnostic procedures, 42 pathologic results were found with 131I-hippurate clearance, while only 14 abnormal results were detected by static 99mTc-DMSA scans. Hippurate clearance is thus a sensitive method of functional renal evaluation in PSS.
肾脏受累是进行性系统性硬化症（PSS）最常见的死亡原因之一。因此，在PSS中尽早发现潜在的肾功能损害非常重要。在76例接受核医学诊断程序的患者中，131I-马尿酸盐清除率检查发现42例病理结果，而静态99mTc-DMSA扫描仅检测到14例异常结果。因此，马尿酸盐清除率是评估PSS患者肾功能的一种敏感方法。
