Puschmann M, Gogoll K
Alfred Marchionini Stiftung, Reinbek.
Hautarzt. 1989;40 Suppl 9:67-70.
A significant increase in skin moisture and an improvement in skin smoothness after application of a urea-containing cream was noticed in a large number of volunteers with healthy skin and in neurodermitis patients compared with untreated skin and with vehicle. The effect was shown after one application (short-term test) as well as after repeated application (long-term test). Regular application of preparation containing urea increases the moisture of a the skin and improves the skin's smoothness compared with its previous condition, with untreated skin, and with placebo preparations.
与未处理的皮肤和赋形剂相比，大量健康皮肤志愿者和神经性皮炎患者在使用含尿素乳膏后，皮肤水分显著增加，皮肤光滑度得到改善。一次涂抹后（短期测试）以及重复涂抹后（长期测试）均显示出该效果。与之前的皮肤状况、未处理的皮肤以及安慰剂制剂相比，定期使用含尿素制剂可增加皮肤水分并改善皮肤光滑度。
