Boeras Debrah I, Nkengasong John N, Peeling Rosanna W
aLondon School of Hygiene and Tropical Medicine, London, UK bUS Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Curr Opin HIV AIDS. 2017 Mar;12(2):171-174. doi: 10.1097/COH.0000000000000349.
Recent advances in point-of-care technologies to ensure universal access to affordable quality-assured diagnostics have the potential to transform patient management, surveillance programmes, and control of infectious diseases. Decentralization of testing can put tremendous stresses on fragile health systems if the laboratory is not involved in the planning, introduction, and scale-up strategies.
The impact of investments in novel technologies can only be realized if these tests are evaluated, adopted, and scaled up within the healthcare system with appropriate planning and understanding of the local contexts in which these technologies will be used.
In this digital age, the laboratory needs to take on the role of the Command Centre for technology introduction and implementation. Implementation science is needed to understand the political, cultural, economic, and behavioural context for technology introduction. The new paradigm should include: building a comprehensive system of laboratories and point-of-care testing sites to provide quality-assured diagnostic services with good laboratory-clinic interface to build trust in test results and linkage to care; building and coordinating a comprehensive national surveillance and communication system for disease control and global health emergencies; conducting research to monitor the impact of new tools and interventions on improving patient care.
即时检测技术的最新进展有望确保普遍获得价格合理且质量有保证的诊断方法,从而改变患者管理、监测计划以及传染病控制。如果实验室不参与检测的规划、引入和扩大规模策略,检测的分散化可能会给脆弱的卫生系统带来巨大压力。
只有在医疗系统内对这些检测进行评估、采用并扩大规模,并对这些技术的使用当地情况有适当规划和了解,对新技术的投资影响才能实现。
在这个数字时代,实验室需要承担起技术引入和实施指挥中心的角色。需要实施科学来了解技术引入的政治、文化、经济和行为背景。新范式应包括:建立一个由实验室和即时检测点组成的综合系统,以提供质量有保证的诊断服务,并建立良好的实验室与临床接口,以增强对检测结果的信任并与护理建立联系;建立并协调一个全面的国家疾病控制和全球卫生紧急情况监测与通信系统;开展研究以监测新工具和干预措施对改善患者护理的影响。