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Hypusination of eIF5A as a Target for Antiviral Therapy.

作者信息

Olsen Michelle E, Connor John H

机构信息

Department of Microbiology, Boston University , Boston, Massachusetts.

出版信息

DNA Cell Biol. 2017 Mar;36(3):198-201. doi: 10.1089/dna.2016.3611. Epub 2017 Jan 12.

Abstract
摘要

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Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.
J Virol. 2016 Oct 14;90(21):9683-9692. doi: 10.1128/JVI.01347-16. Print 2016 Nov 1.
3
Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication.
mBio. 2016 Jul 26;7(4):e00882-16. doi: 10.1128/mBio.00882-16.
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Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.
Cell Host Microbe. 2016 Aug 10;20(2):167-77. doi: 10.1016/j.chom.2016.06.011. Epub 2016 Jul 14.
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Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.
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Approved Antiviral Drugs over the Past 50 Years.
Clin Microbiol Rev. 2016 Jul;29(3):695-747. doi: 10.1128/CMR.00102-15.
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Repositioning the Old Fungicide Ciclopirox for New Medical Uses.
Curr Pharm Des. 2016;22(28):4443-50. doi: 10.2174/1381612822666160530151209.
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The hypusine-containing translation factor eIF5A.
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