Murray M J
Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Leesburg 22075.
J Am Vet Med Assoc. 1989 Oct 15;195(8):1135-41.
Of 183 foals examined by use of gastroendoscopy during 1987 and 1988, 94 had gastric lesions. Sixty-eight of 120 foals in the 1- to 85-day-old age range had endoscopically confirmed gastric lesions, and 26 of 63 foals in the 90- to 310-day-old age range had gastric lesions. Lesions were observed most frequently in the stratified squamous mucosal epithelium, particularly adjacent to the margo plicatus. Lesions were observed in the gastric glandular mucosa in 26 of the 94 foals with gastric lesions, and with a greater frequency in foals with a clinical disorder than in foals with no disorder (27% vs 3%). In young foals, lesions were consistently observed in the stratified squamous mucosal epithelium adjacent to the margo plicatus along the greater curvature of the stomach at 2 specific sites. These lesions were frequently associated with desquamation of the stratified squamous mucosal epithelium, which was observed in 69 of the 82 foals less than or equal to 30 days old and in 13 of the 101 foals greater than 30 days old. Lesions in the stratified squamous mucosal epithelium adjacent to the margo plicatus were associated with concurrent clinical disorders in foals greater than 90 days old, but developed with identical frequency in foals less than 90 days old with or without a clinical disorder. Lesions in the stratified squamous mucosal epithelium along the lesser curvature of the stomach were observed only in foals with concurrent clinical disorder, and with a higher frequency in foals greater than 90 days old than in younger foals (24% vs 3%).
在1987年和1988年通过胃镜检查的183匹幼驹中，94匹有胃部病变。在1至85日龄的120匹幼驹中，68匹经内镜证实有胃部病变；在90至310日龄的63匹幼驹中，26匹有胃部病变。病变最常出现在复层鳞状黏膜上皮，尤其是靠近褶缘处。在94匹有胃部病变的幼驹中，26匹的胃腺黏膜有病变，有临床疾病的幼驹比无疾病的幼驹出现该病变的频率更高（27%对3%）。在幼驹中，沿着胃大弯在两个特定部位靠近褶缘的复层鳞状黏膜上皮始终存在病变。这些病变常伴有复层鳞状黏膜上皮的脱落，在82匹小于或等于30日龄的幼驹中有69匹出现，在101匹大于30日龄的幼驹中有13匹出现。在大于90日龄的幼驹中，靠近褶缘的复层鳞状黏膜上皮病变与并发的临床疾病有关，但在小于90日龄有或无临床疾病的幼驹中出现频率相同。仅在并发临床疾病的幼驹中观察到沿着胃小弯的复层鳞状黏膜上皮病变，大于90日龄的幼驹比年幼幼驹出现频率更高（24%对3%）。
