Department of Otolaryngology, Dışkapı Yıldırım Beyazıt Research and Training Hospital, Ankara, Turkey.
Department of Otolaryngology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey.
Turk J Med Sci. 2016 Dec 20;46(6):1749-1754. doi: 10.3906/sag-1512-52.
BACKGROUND/AIM: The aim of this study was to investigate alterations in voice parameters among patients using continuous positive airway pressure (CPAP) for the treatment of obstructive sleep apnea syndrome.
Patients with an indication for CPAP treatment without any voice problems and with normal laryngeal findings were included and voice parameters were evaluated before and 1 and 6 months after CPAP. Videolaryngostroboscopic findings, a self-rated scale (Voice Handicap Index-10, VHI-10), perceptual voice quality assessment (GRBAS: grade, roughness, breathiness, asthenia, strain), and acoustic parameters were compared.
Data from 70 subjects (48 men and 22 women) with a mean age of 44.2 ± 6.0 years were evaluated. When compared with the pre-CPAP treatment period, there was a significant increase in the VHI-10 score after 1 month of treatment and in VHI- 10 and total GRBAS scores, jitter percent (P = 0.01), shimmer percent, noise-to-harmonic ratio, and voice turbulence index after 6 months of treatment. Vague negative effects on voice parameters after the first month of CPAP treatment became more evident after 6 months.
We demonstrated nonsevere alterations in the voice quality of patients under CPAP treatment. Given that CPAP is a long-term treatment it is important to keep these alterations in mind.
背景/目的：本研究旨在探讨阻塞性睡眠呼吸暂停综合征患者使用持续气道正压通气（CPAP）治疗后嗓音参数的变化。
纳入了无嗓音问题且喉检查正常、有 CPAP 治疗适应证的患者，并在 CPAP 治疗前、治疗后 1 个月和 6 个月评估了嗓音参数。比较了频闪喉镜检查结果、自我评估量表（嗓音障碍指数-10，VHI-10）、感知嗓音质量评估（GRBAS：等级、粗糙、气息、无力、紧张）和声学参数。
共评估了 70 例患者（48 例男性和 22 例女性）的数据，平均年龄为 44.2±6.0 岁。与 CPAP 治疗前相比，治疗 1 个月后 VHI-10 评分、治疗 6 个月后 VHI-10 和总 GRBAS 评分、抖动百分比（P=0.01）、颤抖百分比、噪声与谐波比和嗓音湍流指数均显著增加。CPAP 治疗 1 个月后对嗓音参数的模糊负面影响在 6 个月后变得更加明显。
我们证明了 CPAP 治疗患者的嗓音质量发生了非严重变化。鉴于 CPAP 是一种长期治疗方法，有必要注意这些变化。
