Gupta Vishal, Gupta Somesh
Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Int J STD AIDS. 2017 Aug;28(9):940-942. doi: 10.1177/0956462416688159. Epub 2017 Jan 12.
Several factors such as genetic susceptibility, autoimmunity, hormones, infections, local trauma, urine, and occlusion have been speculated to play a role in the pathogenesis of lichen sclerosus. We report two male patients with lichen sclerosus around 'ectopic' urethral openings and the opposing surfaces of the penile shaft and scrotum, providing further evidence in support of urine and occlusion as contributing factors in the development of lichen sclerosus.
遗传易感性、自身免疫、激素、感染、局部创伤、尿液及阻塞等多种因素被推测在硬化性苔藓的发病机制中起作用。我们报告了两名男性患者，他们在“异位”尿道口周围以及阴茎体和阴囊的相对表面患有硬化性苔藓，为尿液和阻塞作为硬化性苔藓发病的促成因素提供了进一步证据。
