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膝关节内侧骨关节炎行胫骨高位开放楔形截骨术后的良好功能结果:一项平均随访8.3年的前瞻性研究。

Good functional results following high tibial opening-wedge osteotomy of knees with medial osteoarthritis: A prospective study with a mean of 8.3years of follow-up.

作者信息

Ekeland Arne, Nerhus Tor Kjetil, Dimmen Sigbjørn, Thornes Elisabeth, Heir Stig

机构信息

Martina Hansens Hospital, Box 823, N-1306 Sandvika, Norway.

Martina Hansens Hospital, Box 823, N-1306 Sandvika, Norway.

出版信息

Knee. 2017 Mar;24(2):380-389. doi: 10.1016/j.knee.2016.12.005. Epub 2017 Jan 9.

Abstract

BACKGROUND

To report time dependent functional improvement and predictive risk factors for failure when the load in varus knees with medial osteoarthritis is shifted from the medial to the lateral knee compartment.

METHODS

Forty-nine consecutive patients (52 knees), mean age 47 (31-64) years, underwent a high tibial opening-wedge valgus osteotomy stabilized with a Puddu plate and bone grafting. The patients were evaluated with the Knee Injury and Osteoarthritis Outcome Score (KOOS) preoperatively and at three and six months, one, two, five and 10years postoperatively with a mean follow-up time of 8.3years (2.0-10.6).

RESULTS

Mean angular correction was 8.0° (four to 12). The five subscores of KOOS increased significantly during the first year by 40-131% from preoperative values, the good results remaining throughout the 10-year follow-up for those with a surviving osteotomy. The outcome was related to the grade of preoperative osteoarthritis. Seven knees were converted to total knee arthroplasty (TKA) mean 6.2years (two to nine) post-operatively, and had a lower KOOS preoperatively than those of surviving osteotomies. The osteotomy survival rate at five years was 94% and at 10years 83%. Patients with KOOS subscore quality of life (QoL) <44 at the two-year follow-up had a 11.7 times higher risk for later TKA than those with QoL ≥44 (P=0.017).

CONCLUSION

High tibial opening-wedge osteotomy for medial knee osteoarthritis resulted in good functional recovery after one year and favorable mid-term results. It may be a good treatment option for middle-aged patients with varus knees and medial osteoarthritis in order to prevent or postpone TKA.

摘要

背景

报告内侧骨关节炎的内翻膝关节负荷从内侧向外侧膝关节腔转移时,随时间变化的功能改善情况以及失败的预测风险因素。

方法

49例连续患者(52个膝关节),平均年龄47岁(31 - 64岁),接受了用普杜钢板固定和植骨的高位胫骨开放楔形外翻截骨术。术前以及术后3个月、6个月、1年、2年、5年和10年采用膝关节损伤和骨关节炎疗效评分(KOOS)对患者进行评估,平均随访时间为8.3年(2.0 - 10.6年)。

结果

平均角度矫正为8.0°(4°至12°)。KOOS的五个子评分在第一年显著增加,较术前值提高了40% - 131%,对于截骨术成功的患者,在整个10年随访期间效果良好。结果与术前骨关节炎的分级有关。7个膝关节在术后平均6.2年(2至9年)改行全膝关节置换术(TKA),其术前KOOS评分低于截骨术成功的患者。5年时截骨术生存率为94%,10年时为83%。在两年随访时KOOS子评分生活质量(QoL)<44的患者,后期行TKA的风险比QoL≥44的患者高11.7倍(P = 0.017)。

结论

内侧膝关节骨关节炎的高位胫骨开放楔形截骨术在1年后功能恢复良好,中期效果良好。对于内翻膝关节和内侧骨关节炎的中年患者,它可能是预防或推迟TKA的良好治疗选择。

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