Department of Neurosurgery, Pontchaillou University Hospital, Rennes, France.
Department of Hospital Infection Control, Pontchaillou University Hospital, Rennes, France.
J Hosp Infect. 2017 Feb;95(2):144-147. doi: 10.1016/j.jhin.2016.11.019. Epub 2016 Dec 7.
In a controlled before-and-after study in a single centre, it was aimed to determine whether identification of Staphylococcus aureus nasal carriers followed by nasal mupirocin ointment and chlorhexidine soap reduced surgical site infections (SSIs) among 182 patients undergoing deep brain stimulation. In all, 119 patients were included in the control group and 63 in the screening group. There was a significant SSI decrease from 10.9% to 1.6% between the two groups (P<0.04; relative risk: 0.13; 95% confidence interval: 0.003-0.922). There were eight SSIs involving S. aureus in the control group, none in the screening group. No specific risk factors for SSI were identified.
在单中心的一项对照前后研究中，旨在确定对 182 名接受深部脑刺激的患者进行金黄色葡萄球菌鼻腔携带者鉴定，然后使用莫匹罗星软膏和洗必泰皂进行鼻腔处理，是否可以降低手术部位感染 (SSI)。共有 119 名患者纳入对照组，63 名患者纳入筛查组。两组之间 SSI 发生率从 10.9%显著下降至 1.6%（P<0.04；相对风险：0.13；95%置信区间：0.003-0.922）。对照组有 8 例 SSI 涉及金黄色葡萄球菌，筛查组无 1 例。未确定 SSI 的特定危险因素。
