Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China.
Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China.
Int J Infect Dis. 2017 Feb;55:72-80. doi: 10.1016/j.ijid.2016.12.028. Epub 2017 Jan 7.
To identify the barriers to and enablers of the prevention of mother-to-child transmission (PMTCT) of HIV program in China.
A systematic review of the existing literature regarding barriers to and enablers of the implementation of the PMTCT program in China was performed. The checklist from the SURE guidelines (Supporting the Use of Research Evidence) was used to synthesize the barriers and enablers (supporting strategies) and to analyze their relationships. The HIV testing rate, vertical transmission rate, and antiretroviral treatment (ART) acceptance rate among HIV-infected women and their infants was also extracted from the included studies to assess the effectiveness of the enablers.
Initially 794 publications were identified, and ultimately 14 articles were included. Eighteen types of barrier and nine types of supportive strategy were identified, mainly at the level of social and political issues, healthcare recipients, healthcare providers, and the healthcare system. Based on government-oriented multi-sector cooperation, enablers in China have included community-hospital-family promotion, comprehensive financial support for service recipients, free HIV testing at marriage registration, the opt-out model, and the one-to-one service model.
Experience in China suggests that the government's role in coordination and the acceptability and accessibility of the service should be the primary concerns in regard to the PMTCT project.
确定中国预防母婴传播(PMTCT)艾滋病毒项目的障碍因素和促进因素。
对中国 PMTCT 项目实施的障碍因素和促进因素的现有文献进行系统综述。使用 SURE 指南(支持研究证据的使用)的清单综合障碍因素和促进因素(支持策略),并分析它们之间的关系。从纳入的研究中还提取了 HIV 感染妇女及其婴儿的 HIV 检测率、垂直传播率和抗逆转录病毒治疗(ART)接受率,以评估促进因素的效果。
最初确定了 794 篇出版物,最终纳入了 14 篇文章。确定了 18 种障碍因素和 9 种支持策略,主要涉及社会和政治问题、医疗保健接受者、医疗保健提供者和医疗保健系统层面。基于以政府为导向的多部门合作,中国的促进因素包括社区-医院-家庭推广、为服务接受者提供全面的财务支持、婚姻登记时免费的 HIV 检测、选择退出模式和一对一服务模式。
中国的经验表明,政府在协调方面的作用以及服务的可接受性和可及性应该是 PMTCT 项目的主要关注点。