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一项针对急性冠状动脉综合征患者的积极心理学干预:治疗开发与概念验证试验。

A Positive Psychology Intervention for Patients with an Acute Coronary Syndrome: Treatment Development and Proof-of-Concept Trial.

作者信息

Huffman Jeff C, Millstein Rachel A, Mastromauro Carol A, Moore Shannon V, Celano Christopher M, Bedoya C Andres, Suarez Laura, Boehm Julia K, Januzzi James L

机构信息

Department of Psychiatry, Massachusetts General Hospital, 55 Fruit Street/Blake 11, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

Department of Psychology, Chapman University, Orange, CA, USA.

出版信息

J Happiness Stud. 2016 Oct;17(5):1985-2006. doi: 10.1007/s10902-015-9681-1. Epub 2015 Oct 19.

Abstract

Positive psychological constructs are associated with superior outcomes in cardiac patients, but there has been minimal study of positive psychology (PP) interventions in this population. Our objective was to describe the intervention development and pilot testing of an 8-week phone-based PP intervention for patients following an acute coronary syndrome (ACS). Initial intervention development and single-arm proof-of-concept trial, plus comparison of the PP intervention to a subsequently-recruited treatment as usual (TAU) cohort. PP development utilized existing literature, expert input, and qualitative interview data in ACS patients. In the proof-of-concept trial, the primary outcomes were feasibility and acceptability, measured by rates of exercise completion and participant ratings of exercise ease/utility. Secondary outcomes were pre-post changes in psychological outcomes and TAU comparisons, measured using effect sizes (Cohen's ). The PP intervention and treatment manual were successfully created. In the proof-of-concept trial, 17/23 PP participants (74 %) completed at least 5 of 8 exercises. Participants rated the ease ( = 7.4/10; = 2.1) and utility ( = 8.1/10, = 1.6) of PP exercises highly. There were moderate pre-post improvements (s = .46-.69) in positive affect, anxiety, and depression, but minimal effects on dispositional optimism ( = .08). Compared to TAU participants ( = 22), PP participants demonstrated greater improvements in positive affect, anxiety, and depression (s = . 47-.71), but not optimism. A PP intervention was feasible, well-accepted, and associated with improvements in most psychological measures among cardiac patients. These results provide support for a larger trial focusing on behavioral outcomes.

摘要

积极的心理建构与心脏病患者的更好预后相关,但针对这一人群的积极心理学(PP)干预研究极少。我们的目标是描述一项针对急性冠状动脉综合征(ACS)患者的为期8周的基于电话的PP干预措施的干预开发及试点测试情况。初始干预开发及单组概念验证试验,再加上将PP干预措施与随后招募的常规治疗(TAU)队列进行比较。PP干预措施的开发利用了现有文献、专家意见以及ACS患者的定性访谈数据。在概念验证试验中,主要结局指标为可行性和可接受性,通过运动完成率以及参与者对运动难易程度/效用的评分来衡量。次要结局指标为心理结局指标的前后变化以及与TAU的比较,采用效应量(科恩d值)进行测量。成功创建了PP干预措施及治疗手册。在概念验证试验中,23名PP参与者中有17名(74%)完成了8项运动中的至少5项。参与者对PP运动的难易程度(均值 = 7.4/10;标准差 = 2.1)和效用(均值 = 8.1/10,标准差 = 1.6)评价很高。积极情绪、焦虑和抑郁方面有中度的前后改善(效应量 = 0.46 - 0.69),但对特质乐观的影响极小(效应量 = 0.08)。与TAU参与者(n = 22)相比,PP参与者在积极情绪、焦虑和抑郁方面有更大改善(效应量 = 0.47 - 0.71),但在乐观方面没有差异。一项PP干预措施是可行的、广受接受的,并且与心脏病患者大多数心理指标的改善相关。这些结果为一项关注行为结局的更大规模试验提供了支持。

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