Alim Nural Erzurum, Kiziltan Gul
Nural Erzurum Alim, Ph.D. Republic of Turkey Ministry of Health, Turkey Public Health Institutions, Department of Cancer, Sihhiye, Ankara, Turkey.
Prof. Gul Kiziltan, Department of Nutrition and Dietetics, Baskent University of Health Science Faculty, Etimesgut, Ankara, Turkey.
Pak J Med Sci. 2016 Nov-Dec;32(6):1537-1542. doi: 10.12669/pjms.326.11346.
To determine the risk factors of obesity and diet on breast cancer in Ankara, Turkey.
A case-controlled study was carried out on newly diagnosed 40 breast cancer patients [patient group (PC)] and 40 volunteer individuals [control group (CG)] with no diagnosis of cancer and history of cancer in the family with similar characteristics to the age and gender-matched patient group between March and July 2016. All the individuals were administered a questionnaire by face-to-face interview method.
The mean menarche age, age at first birth and menopause age were 13.0±1.17, 22.6±3.78 and 44.33±2.39 years in PG and 12.3±0.95, 21.6±2.99, 46.71±2.41 years in CG, respectively. The mean BMI values were determined as 28.1±6.75 kg/m in PG and 30.1±6.18 kg/m in CG (p>0.05). It was determined that intake of vitamin C and fiber decreases the risk of breast cancer. Also, eating quickly and smoking were risk factors for breast cancer (p<0.05).
This study indicated that there are relationships between menarche age, menopause age, and age at first birth, eating quickly, smoking and breast cancer. Conversely, there are significant negative relationships between dietary fiber, vitamin C intake and breast cancer. As a result, it can be said that there is a link between breast cancer and lifestyle factors and a reduction in the risk of developing breast cancer can be achieved through changes in diet, one of the lifestyle factors.
确定土耳其安卡拉肥胖及饮食因素与乳腺癌的风险关系。
2016年3月至7月,对40例新诊断的乳腺癌患者[患者组(PC)]和40例无癌症诊断且家族无癌症病史、年龄和性别与患者组匹配的志愿者个体[对照组(CG)]进行病例对照研究。所有个体均通过面对面访谈的方式填写问卷。
患者组的初潮平均年龄、首次生育年龄和绝经年龄分别为13.0±1.17岁、22.6±3.78岁和44.33±2.39岁,对照组分别为12.3±0.95岁、21.6±2.99岁和46.71±2.41岁。患者组的平均体重指数(BMI)值为28.1±6.75kg/m,对照组为30.1±6.18kg/m(p>0.05)。研究发现,维生素C和纤维的摄入可降低患乳腺癌的风险。此外,进食速度快和吸烟是患乳腺癌的风险因素(p<0.05)。
本研究表明,初潮年龄、绝经年龄、首次生育年龄、进食速度快、吸烟与乳腺癌之间存在关联。相反,膳食纤维、维生素C的摄入与乳腺癌之间存在显著的负相关关系。因此,可以说乳腺癌与生活方式因素之间存在联系,通过改变饮食这一生活方式因素之一,可以降低患乳腺癌的风险。