Thamburaj Krishnamoorthy, Cockroft Kevin, Agarwal Amit K, Sabat Shyam, Kalapos Paul
Neuroradiology, Penn State Hershey Medical Center.
Department of Neurosurgery, Penn State Hershey Medical Center.
Cureus. 2016 Dec 2;8(12):e909. doi: 10.7759/cureus.909.
To identify the effective magnetic resonance angiography (MRA) technique to monitor intracranial aneurysms treated with stent-assisted coiling.
Retrospective analysis of various MRA techniques was performed in 42 patients. Three neuroradiologists independently compared non-contrast time of flight (ncTOF) MRA of the head, contrast-enhanced time of flight (cTOF) MRA of the head and dynamic contrast-enhanced MRA (CEMRA) of the head and neck or of the head. Digital subtraction angiography (DSA) was available for comparison in 32 cases. Inter-rater agreement (kappa statistic) was assessed.
Artifactual in-stent severe stenosis or flow gap was identified by ncTOF MRA in 23 of 42 cases (55%) and by cTOF MRA in 23 of 38 cases (60%). DSA excluded in-stent stenosis or occlusion in all 32 cases. No difference was noted between ncTOF and cTOF in the demonstration of neck remnants or residual aneurysms in three cases each. CEMRA of the head and neck or of the head was rated superior to ncTOF and cTOF MRA by all three investigators in seven out of eight cases. In one case, all three techniques demonstrated signifcant artifacts due to double stent placement during coiling. The kappa statistic revealed 0.8 agreement between investigators.
In the assessment of stent-assisted coiling of intracranial aneurysm, both ncTOF and cTOF MRA show similar results. CEMRA tends to show better flow signals in stent and residual aneurysm.
确定用于监测支架辅助弹簧圈栓塞治疗颅内动脉瘤的有效磁共振血管造影(MRA)技术。
对42例患者的各种MRA技术进行回顾性分析。三位神经放射科医生独立比较头部非对比时间飞跃(ncTOF)MRA、头部对比增强时间飞跃(cTOF)MRA以及头部和颈部或头部的动态对比增强MRA(CEMRA)。32例患者可进行数字减影血管造影(DSA)用于对比。评估评分者间一致性(kappa统计量)。
42例中的23例(55%)通过ncTOF MRA发现支架内存在伪像性严重狭窄或血流间隙,38例中的23例(60%)通过cTOF MRA发现。DSA排除了所有32例中的支架内狭窄或闭塞。ncTOF和cTOF在显示三例颈部残余或残余动脉瘤方面无差异。在八例中的七例中,三位研究者均认为头部和颈部或头部的CEMRA优于ncTOF和cTOF MRA。在一例中,由于栓塞过程中放置了双支架,所有三种技术均显示出明显伪像。kappa统计量显示研究者间一致性为0.8。
在评估颅内动脉瘤的支架辅助弹簧圈栓塞时,ncTOF和cTOF MRA显示出相似的结果。CEMRA在支架和残余动脉瘤中往往显示出更好的血流信号。