Habermehl D, Habl G, Eckstein H-H, Meisner F, Combs S E
Klinik für RadioOnkologie und Strahlentherapie, Klinikum rechts der Isar, TU München, Ismaninger Str. 22, 81675, München, Deutschland.
Institut für Innovative Radiotherapie (IRT), Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Oberschleißheim, Deutschland.
Chirurg. 2017 Apr;88(4):311-316. doi: 10.1007/s00104-016-0352-5.
Lymphatic fistulas and lymphoceles are known complications after vascular surgery of the groin and after extended surgical interventions in the pelvic region. Unfortunately, conservative standard therapies are not always successful.
Evaluation of the therapeutic efficacy and related side effects of percutaneous low-dose irradiation in patients with lymphorrhea and definition of its importance.
Current presentation of previously published case series, reviews and guidelines.
The use of low-dose irradiation therapy with single doses of 0.3-0.5 Gy leads to a cessation of the lymphatic flow in a high percentage of patients when standard therapies do not show a sufficient effect. With cessation of lymphorrhea irradiation should be terminated. Acute side effects have not been reported and the risk of tumor induction is almost negligible.
Low-dose irradiation is an effective and very well-tolerated therapeutic alternative in the treatment of lymphatic fistulas and lymphorrhea when conservative therapies are unsuccessful.
淋巴管瘘和淋巴囊肿是腹股沟血管手术后以及盆腔区域广泛手术干预后的已知并发症。不幸的是，保守的标准治疗方法并不总是成功的。
评估经皮低剂量照射对淋巴漏患者的治疗效果及相关副作用，并确定其重要性。
当前已发表的病例系列、综述和指南。
当标准治疗效果不佳时，单次剂量为0.3 - 0.5 Gy的低剂量照射疗法可使高比例患者的淋巴液流动停止。淋巴漏停止后应终止照射。尚未报告急性副作用，诱发肿瘤的风险几乎可以忽略不计。
当保守治疗失败时，低剂量照射是治疗淋巴管瘘和淋巴漏的一种有效且耐受性良好的治疗选择。
