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“门诊”与“住院”全髋关节置换术(THA)和全膝关节置换术(TKA)的定义差异会影响研究结果。

Definitional Differences of 'Outpatient' Versus 'Inpatient' THA and TKA Can Affect Study Outcomes.

作者信息

Bovonratwet Patawut, Webb Matthew L, Ondeck Nathaniel T, Lukasiewicz Adam M, Cui Jonathan J, McLynn Ryan P, Grauer Jonathan N

机构信息

Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, 47 College Street, New Haven, CT, 06520, USA.

Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Clin Orthop Relat Res. 2017 Dec;475(12):2917-2925. doi: 10.1007/s11999-017-5236-6.

Abstract

BACKGROUND

There has been great interest in performing outpatient THA and TKA. Studies have compared such procedures done as outpatients versus inpatients. However, stated "outpatient" status as defined by large national databases such as the National Surgical Quality Improvement Program (NSQIP) may not be a consistent entity, and the actual lengths of stay of those patients categorized as outpatients in NSQIP have not been specifically ascertained and may in fact include some patients who are "observed" for one or more nights. Current regulations in the United States allow these "observed" patients to stay more than one night at the hospital under observation status despite being coded as outpatients. Determining the degree to which this is the case, and what, exactly, "outpatient" means in the NSQIP, may influence the way clinicians read studies from that source and the way hospital systems and policymakers use those data.

QUESTIONS/PURPOSES: The purposes of this study were (1) to utilize the NSQIP database to characterize the differences in definition of "inpatient" and "outpatient" (stated status versus actual length of stay [LOS], measured in days) for THA and TKA; and (2) to study the effect of defining populations using different definitions.

METHODS

Patients who underwent THA and TKA in the 2005 to 2014 NSQIP database were identified. Outpatient procedures were defined as either hospital LOS = 0 days in NSQIP or being termed "outpatient" by the hospital. The actual hospital LOS of "outpatients" was characterized. "Outpatients" were considered to have stayed overnight if they had a LOS of 1 day or longer. The effects of the different definitions on 30-day outcomes were evaluated using multivariate analysis while controlling for potential confounding factors.

RESULTS

Of 72,651 patients undergoing THA, 529 were identified as "outpatients" but only 63 of these (12%) had a LOS = 0. Of 117,454 patients undergoing TKA, 890 were identified as "outpatients" but only 95 of these (11%) had a LOS = 0. After controlling for potential confounding factors such as gender, body mass index, functional status before surgery, comorbidities, and smoking status, we found "inpatient" THA to be associated with increased risk of any adverse event (relative risk, 2.643, p = 0.002), serious adverse event (relative risk, 2.455, p = 0.011), and readmission (relative risk, 2.775, p = 0.010) compared with "outpatient" THA. However, for the same procedure and controlling for the same factors, patients who had LOS > 0 were not associated with any increased risk compared with patients who had LOS = 0. A similar trend was also found in the TKA cohort.

CONCLUSIONS

Future THA, TKA, or other investigations on this topic should consistently quantify the term "outpatient" because different definitions, stated status or actual LOS, may lead to different assignments of risk factors for postoperative complications. Accurate data regarding risk factors for complications after total joint arthroplasty are crucial for efforts to reduce length of hospital stay and minimize complications.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

门诊全髋关节置换术(THA)和全膝关节置换术(TKA)备受关注。已有研究比较了门诊手术与住院手术的情况。然而,像国家外科质量改进计划(NSQIP)这样的大型国家级数据库所定义的“门诊”状态可能并非一个统一的概念,NSQIP中被归类为门诊患者的实际住院时长尚未得到具体确定,实际上可能包括一些被“观察”一两个晚上的患者。美国现行法规允许这些“被观察”的患者尽管被编码为门诊患者,但仍可在医院观察状态下停留超过一晚。确定这种情况的程度以及NSQIP中“门诊”的确切含义,可能会影响临床医生解读该来源研究的方式以及医院系统和政策制定者使用这些数据的方式。

问题/目的:本研究的目的是:(1)利用NSQIP数据库描述THA和TKA中“住院患者”和“门诊患者”定义的差异(申报状态与实际住院时长[LOS],以天为单位衡量);(2)研究使用不同定义界定人群的影响。

方法

在2005年至2014年NSQIP数据库中识别接受THA和TKA的患者。门诊手术在NSQIP中定义为住院时长 = 0天或被医院称为“门诊患者”。对“门诊患者”的实际住院时长进行了描述。如果“门诊患者”的住院时长为1天或更长,则被视为过夜。在控制潜在混杂因素的同时,使用多变量分析评估不同定义对30天结局的影响。

结果

在72,651例接受THA的患者中,529例被确定为“门诊患者”,但其中只有63例(12%)住院时长 = 0。在117,454例接受TKA的患者中,890例被确定为“门诊患者”,但其中只有95例(11%)住院时长 = 0。在控制了性别、体重指数、术前功能状态、合并症和吸烟状态等潜在混杂因素后,我们发现与“门诊”THA相比,“住院”THA发生任何不良事件(相对风险,2.643,p = 0.002)、严重不良事件(相对风险,2.455,p = 0.011)和再入院(相对风险2.775,p = 0.010)的风险增加。然而,对于相同的手术并控制相同的因素,住院时长 > 0的患者与住院时长 = 0的患者相比,未发现任何风险增加。在TKA队列中也发现了类似趋势。

结论

未来关于THA、TKA或该主题的其他研究应始终对“门诊患者”一词进行量化,因为不同的定义,即申报状态或实际住院时长,可能导致术后并发症危险因素的不同分配。全关节置换术后并发症危险因素的准确数据对于缩短住院时长和减少并发症的努力至关重要。

证据水平

三级,治疗性研究。

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