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[痴呆与共病情况]

[Dementia and comorbid conditions].

作者信息

Hofmann W

机构信息

Geriatrisches Zentrum Neumünster & Bad Bramstedt, Friesenstr. 11, 24534, Neumünster, Deutschland.

出版信息

Internist (Berl). 2017 Feb;58(2):105-116. doi: 10.1007/s00108-016-0182-z.

DOI:10.1007/s00108-016-0182-z
PMID:28084503
Abstract

Dementia belongs to the most frequently occurring problems among older patients. For most types of dementia no causal therapy is currently available. Comorbid somatic conditions in patients with dementia are the rule rather than the exception. These potentially modifiable conditions are of major interest and they can therefore play an important role. This includes the strict management of risk factors as well as the avoidance of drugs with delirogenic, anticholinergic and dementing side effects. Thus, treatment of delirium, hypertension, heart failure, anemia, diabetes is important to reduce the symptoms of dementia itself. Possible therapeutic treatment options are described.

摘要

痴呆症是老年患者中最常见的问题之一。目前,大多数类型的痴呆症尚无因果疗法。痴呆症患者合并躯体疾病是普遍现象而非个别情况。这些潜在可改变的状况备受关注,因此可能发挥重要作用。这包括严格管理风险因素以及避免使用具有致谵妄、抗胆碱能和致痴呆副作用的药物。因此,治疗谵妄、高血压、心力衰竭、贫血、糖尿病对于减轻痴呆症本身的症状很重要。文中描述了可能的治疗选择。

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Internist (Berl). 2019 Jul;60(7):761-768. doi: 10.1007/s00108-019-0625-4.

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[Discontinuation of benzodiazepines in old age : When and if so, how?].[老年患者停用苯二氮䓬类药物:何时以及如果要停用,该如何做?]
Z Gerontol Geriatr. 2017 Feb;50(2):115-122. doi: 10.1007/s00391-016-1171-5. Epub 2017 Jan 19.
2
Significance of frailty for predicting adverse clinical outcomes in different patient groups with specific medical conditions.衰弱对预测患有特定疾病的不同患者群体不良临床结局的意义。
Z Gerontol Geriatr. 2016 Oct;49(7):567-572. doi: 10.1007/s00391-016-1128-8. Epub 2016 Sep 14.
3
[Cognitive dysfunction in cardiovascular diseases].
[心血管疾病中的认知功能障碍]
Dtsch Med Wochenschr. 2016 Aug;141(17):1217-21. doi: 10.1055/s-0042-108683. Epub 2016 Aug 24.
4
[Neurocognitive disorders in old age : Role of pharmacotherapy in prevention and treatment].[老年神经认知障碍:药物治疗在预防和治疗中的作用]
Internist (Berl). 2016 Oct;57(10):1029-1036. doi: 10.1007/s00108-016-0097-8.
5
[Anaemia in the elderly].[老年人贫血]
Dtsch Med Wochenschr. 2016 Jul;141(13):954-9. doi: 10.1055/s-0041-103349. Epub 2016 Jun 30.
6
Effects of Disease Burden and Functional Adaptation on Morbidity and Mortality on Older Adults.疾病负担和功能适应对老年人发病率和死亡率的影响。
J Am Geriatr Soc. 2016 Jun;64(6):1242-9. doi: 10.1111/jgs.14163.
7
Identifying Patterns of Multimorbidity in Older Americans: Application of Latent Class Analysis.识别美国老年人的多种慢性病模式:潜在类别分析的应用
J Am Geriatr Soc. 2016 Aug;64(8):1668-73. doi: 10.1111/jgs.14201. Epub 2016 Jun 16.
8
[Connections between sleep and Alzheimer's disease : Insomnia, amnesia and amyloid].睡眠与阿尔茨海默病之间的联系:失眠、失忆与淀粉样蛋白
Nervenarzt. 2017 Mar;88(3):215-221. doi: 10.1007/s00115-016-0122-0.
9
Diagnosis and Disruption: Population-Level Analysis Identifying Points of Care at Which Transitions Are Highest for People with Dementia and Factors That Contribute to Them.诊断与干预:人群水平分析确定痴呆患者发生转归的最高护理点及促成因素
J Am Geriatr Soc. 2016 Mar;64(3):569-77. doi: 10.1111/jgs.14033.
10
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings.改善基层医疗和社区环境中患有多种疾病患者预后的干预措施。
Cochrane Database Syst Rev. 2016 Mar 14;3(3):CD006560. doi: 10.1002/14651858.CD006560.pub3.