Hofmann W
Geriatrisches Zentrum Neumünster & Bad Bramstedt, Friesenstr. 11, 24534, Neumünster, Deutschland.
Internist (Berl). 2017 Feb;58(2):105-116. doi: 10.1007/s00108-016-0182-z.
Dementia belongs to the most frequently occurring problems among older patients. For most types of dementia no causal therapy is currently available. Comorbid somatic conditions in patients with dementia are the rule rather than the exception. These potentially modifiable conditions are of major interest and they can therefore play an important role. This includes the strict management of risk factors as well as the avoidance of drugs with delirogenic, anticholinergic and dementing side effects. Thus, treatment of delirium, hypertension, heart failure, anemia, diabetes is important to reduce the symptoms of dementia itself. Possible therapeutic treatment options are described.
痴呆症是老年患者中最常见的问题之一。目前,大多数类型的痴呆症尚无因果疗法。痴呆症患者合并躯体疾病是普遍现象而非个别情况。这些潜在可改变的状况备受关注,因此可能发挥重要作用。这包括严格管理风险因素以及避免使用具有致谵妄、抗胆碱能和致痴呆副作用的药物。因此,治疗谵妄、高血压、心力衰竭、贫血、糖尿病对于减轻痴呆症本身的症状很重要。文中描述了可能的治疗选择。