Augmenter of liver regeneration: A fundamental life protein.
作者信息
Nalesnik Michael A, Gandhi Chandrashekhar R, Starzl Thomas E
机构信息
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
出版信息
Hepatology. 2017 Jul;66(1):266-270. doi: 10.1002/hep.29047. Epub 2017 May 22.
Abstract
摘要
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Augmenter of liver regeneration: A fundamental life protein.肝脏再生增强因子：一种基本的生命蛋白。
Hepatology. 2017 Jul;66(1):266-270. doi: 10.1002/hep.29047. Epub 2017 May 22.
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Augmenter of liver regeneration links mitochondrial function to steatohepatitis and hepatocellular carcinoma.肝脏再生增强因子将线粒体功能与脂肪性肝炎和肝细胞癌联系起来。
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Deceleration of liver regeneration by knockdown of augmenter of liver regeneration gene is associated with impairment of mitochondrial DNA synthesis in mice.通过敲低肝脏再生增强基因来减缓肝脏再生与小鼠线粒体DNA合成受损有关。
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ALR and liver regeneration.肝再生增强因子与肝再生
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[Augmenter of liver regeneration promotes the proliferation of HL-7702 cells in carbon tetrachloride-induced acute liver injury via increasing autophagy].肝再生增强因子通过增加自噬促进四氯化碳诱导的急性肝损伤中HL-7702细胞的增殖
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Mammalian augmenter of liver regeneration protein is a sulfhydryl oxidase.哺乳动物肝脏再生增强蛋白是一种巯基氧化酶。
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Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.肝再生增强因子缺失通过促进肝星状细胞迁移加速肝纤维化。
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Transient GFER knockdown in vivo impairs liver regeneration after partial hepatectomy.体内短暂敲低GFER会损害部分肝切除术后的肝脏再生。
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Nrf2 activates augmenter of liver regeneration (ALR) via antioxidant response element and links oxidative stress to liver regeneration.Nrf2 通过抗氧化反应元件激活肝再生增强因子 (ALR)，并将氧化应激与肝再生联系起来。
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Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics.肝脏修复与再生的分子机制：从生理学到治疗学
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Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic Steatosis.肝脏再生巴豆酰化增强剂有助于线粒体-内质网接触以减轻肝脂肪变性。
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Loss of nephric augmenter of liver regeneration facilitates acute kidney injury via ACSL4-mediated ferroptosis.肝再生增强因子丢失通过 ACSL4 介导的铁死亡促进急性肾损伤。
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Augmenter of Liver Regeneration Monoclonal Antibody Promotes Apoptosis of Hepatocellular Carcinoma Cells.肝再生增强因子单克隆抗体促进肝癌细胞凋亡
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The protective roles of augmenter of liver regeneration in hepatocytes in the non-alcoholic fatty liver disease.肝脏再生增强因子在非酒精性脂肪性肝病中对肝细胞的保护作用。
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Oxidative Stress and Ischemia/Reperfusion Injury in Kidney Transplantation: Focus on Ferroptosis, Mitophagy and New Antioxidants.肾移植中的氧化应激与缺血/再灌注损伤：聚焦铁死亡、线粒体自噬及新型抗氧化剂
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Molecular pathways of liver regeneration: A comprehensive review.肝脏再生的分子途径：全面综述
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The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways.线粒体膜间隙：线粒体中最狭窄的亚区室，具有最为多样的蛋白质导入途径。
Open Biol. 2021 Mar;11(3):210002. doi: 10.1098/rsob.210002. Epub 2021 Mar 10.
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Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway.肝脏再生增强因子的缺失通过抑制AMPK信号通路破坏小鼠肝脏胆固醇稳态
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Effects of prostaglandin E combined with continuous renal replacement therapy on septic acute kidney injury.前列腺素E联合持续肾脏替代疗法对脓毒症急性肾损伤的影响。
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本文引用的文献
1
Augmenter of Liver Regeneration Gene Therapy Using a Novel Minicircle DNA Vector Alleviates Liver Fibrosis in Rats.
Hum Gene Ther. 2016 Nov;27(11):880-891. doi: 10.1089/hum.2016.006. Epub 2016 May 2.
2
Oxidative folding in the mitochondrial intermembrane space: A regulated process important for cell physiology and disease.线粒体外膜间隙中的氧化折叠：对细胞生理和疾病至关重要的一个受调控过程。
Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1298-306. doi: 10.1016/j.bbamcr.2016.03.023. Epub 2016 Mar 28.
3
Mitochondrial iron overload: causes and consequences.线粒体铁过载：原因与后果
Curr Opin Genet Dev. 2016 Jun;38:31-37. doi: 10.1016/j.gde.2016.02.004. Epub 2016 Mar 25.
4
Srebp2: A master regulator of sterol and fatty acid synthesis.Srebp2：固醇和脂肪酸合成的主要调节因子。
J Lipid Res. 2016 Mar;57(3):333-5. doi: 10.1194/jlr.C066712. Epub 2016 Jan 21.
5
The Level of ALR is Regulated by the Quantity of Mitochondrial DNA.ALR的水平由线粒体DNA的数量调节。
Pathol Oncol Res. 2016 Apr;22(2):431-7. doi: 10.1007/s12253-015-0020-y. Epub 2015 Nov 19.
6
Lipid deposition in liver cells: The influence of short form augmenter of liver regeneration.
Clin Res Hepatol Gastroenterol. 2016 Apr;40(2):186-94. doi: 10.1016/j.clinre.2015.07.004. Epub 2015 Oct 23.
7
Amelioration of nonalcoholic fatty liver disease by hepatic stimulator substance via preservation of carnitine palmitoyl transferase-1 activity.肝刺激物质通过维持肉毒碱棕榈酰转移酶-1 活性改善非酒精性脂肪性肝病。
Am J Physiol Cell Physiol. 2015 Aug 15;309(4):C215-27. doi: 10.1152/ajpcell.00133.2014. Epub 2015 Jun 24.
8
Adrenal Insufficiency in Mitochondrial Disease: A Rare Case of GFER-Related Mitochondrial Encephalomyopathy and Review of the Literature.线粒体疾病中的肾上腺功能不全：一例罕见的与GFER相关的线粒体脑肌病及文献综述
J Child Neurol. 2016 Feb;31(2):190-4. doi: 10.1177/0883073815587327. Epub 2015 May 26.
9
Recombinant human augmenter of liver regeneration protects hepatocyte mitochondrial DNA in rats with obstructive jaundice.重组人肝再生增强因子对梗阻性黄疸大鼠肝细胞线粒体DNA具有保护作用。
J Surg Res. 2015 Jun 1;196(1):90-101. doi: 10.1016/j.jss.2015.02.060. Epub 2015 Mar 4.
10
Augmenter of liver regeneration attenuates inflammation of renal ischemia/reperfusion injury through the NF-kappa B pathway in rats.肝脏再生增强因子通过大鼠的NF-κB途径减轻肾缺血/再灌注损伤的炎症反应。
Int Urol Nephrol. 2015 May;47(5):861-8. doi: 10.1007/s11255-015-0954-8. Epub 2015 Mar 20.
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