动物细胞中星体对胞质分裂刺激作用的一种模型。
A model for astral stimulation of cytokinesis in animal cells.
作者信息
Devore J J, Conrad G W, Rappaport R
机构信息
Department of Electrical and Computer Engineering, Kansas State University, Manhattan 66506.
出版信息
J Cell Biol. 1989 Nov;109(5):2225-32. doi: 10.1083/jcb.109.5.2225.
Abstract
A model is proposed in which stimulation of cortical cytoplasm occurs near the distal ends of astral rays. Levels of stimulation sufficient to cause furrowing occur only in equatorial zones between asters. The model can account for positioning of furrows in very large cells (fertilized eggs of amphibians, birds, and fish) and in cells with several mitotic apparatuses (insects). Finally, the model correctly predicts the positioning and occurrence of furrowing in two experiments in which cellular shape was manipulated into either an hourglass or a cylindrical form before division. These results are consistent with equatorial stimulation theories in which mitotic asters differentially stimulate the future furrow region (equatorial cortex). The results are not consistent with models requiring differential stimulation of nonfurrowing, polar regions of the cell.
摘要
提出了一个模型，其中皮质细胞质的刺激发生在星体射线的远端附近。足以引起沟裂的刺激水平仅发生在星体之间的赤道区域。该模型可以解释非常大的细胞（两栖动物、鸟类和鱼类的受精卵）以及具有多个有丝分裂器的细胞（昆虫）中沟的定位。最后，该模型正确地预测了在两个实验中沟裂的定位和发生情况，在这两个实验中，细胞形状在分裂前被操纵成沙漏形或圆柱形。这些结果与赤道刺激理论一致，在该理论中，有丝分裂星体差异地刺激未来的沟裂区域（赤道皮质）。这些结果与需要对细胞的非沟裂极区进行差异刺激的模型不一致。
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本文引用的文献
1
Experiments concerning the cleavage stimulus in sand dollar eggs.关于海胆卵分裂刺激的实验。
J Exp Zool. 1961 Oct;148:81-9. doi: 10.1002/jez.1401480107.
2
DURATION OF STIMULUS AND LATENT PERIODS PRECEDING FURROW FORMATION IN SAND DOLLAR EGGS.海胆卵形成沟之前刺激的持续时间和潜伏期
J Exp Zool. 1965 Apr;158:373-82. doi: 10.1002/jez.1401580311.
3
Cell division without mitotic apparatus in sea urchin eggs.海胆卵中无有丝分裂器的细胞分裂。
Exp Cell Res. 1956 Dec;11(3):630-6. doi: 10.1016/0014-4827(56)90171-9.
4
Cytokinesis: the effect of initial distance between mitotic apparatus and surface on the rate of subsequent cleavage furrow progress.
J Exp Zool. 1982 Jul 1;221(3):399-403. doi: 10.1002/jez.1402210318.
5
Distribution of tubulin-containing structures in the egg of the sea urchin Strongylocentrotus purpuratus from fertilization through first cleavage.从受精到第一次卵裂期间，紫海胆（Strongylocentrotus purpuratus）卵中含微管蛋白结构的分布。
J Cell Biol. 1980 Mar;84(3):668-79. doi: 10.1083/jcb.84.3.668.
6
Cooperation of kinetochores and pole in the establishment of monopolar mitotic apparatus.着丝粒与纺锤极在单极有丝分裂装置形成中的协作。
Proc Natl Acad Sci U S A. 1981 Jan;78(1):377-81. doi: 10.1073/pnas.78.1.377.
7
Control mechanisms of the cell cycle: role of the spatial arrangement of spindle components in the timing of mitotic events.细胞周期的调控机制：纺锤体组件的空间排列在有丝分裂事件时间安排中的作用。
J Cell Biol. 1983 Sep;97(3):877-86. doi: 10.1083/jcb.97.3.877.
8
On the mechanisms of cytokinesis in animal cells.论动物细胞胞质分裂的机制。
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9
Division of constricted and urethane-treated sand dollar eggs: a test of the polar stimulation hypothesis.
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10
The translational mobility of substances within the cytoplasmic matrix.物质在细胞质基质中的平移流动性。
Proc Natl Acad Sci U S A. 1984 Nov;81(21):6747-51. doi: 10.1073/pnas.81.21.6747.
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