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心脏手术后转运期间手控通气与机械通气的血流动力学后果

Hemodynamic Consequence of Hand Ventilation Versus Machine Ventilation During Transport After Cardiac Surgery.

作者信息

O'Brien E Orestes, Newhouse Beverly J, Cronin Brett, Robbins Kimberly, Nguyen Albert P, Khoche Swapnil, Schmidt Ulrich

机构信息

Department of Anesthesiology, University of California, San Diego, CA.

Department of Anesthesiology, University of California, San Diego, CA.

出版信息

J Cardiothorac Vasc Anesth. 2017 Aug;31(4):1246-1249. doi: 10.1053/j.jvca.2016.11.006. Epub 2016 Nov 9.

Abstract

OBJECTIVES

The hemodynamic consequences of ventilation of intubated patients during transport either by hand or using a transport ventilator have not been reported in patients after cardiac surgery. The authors hypothesized that bag-mask ventilation would alter end-tidal CO during transport and hemodynamic parameters in patients post-cardiac surgery.

DESIGN

A prospective, randomized trial.

SETTING

A university-affiliated tertiary care hospital.

PARTICIPANTS

Cardiac surgery patients.

INTERVENTIONS

Thirty-six patients were randomized to hand ventilation or machine ventilation. Hemodynamic variables including blood pressure, heart rate, peripheral saturation of oxygen, and end-tidal carbon dioxide (ETCO) were measured in these patients prior to transport, every 2 minutes during transport and upon arrival in the intensive care unit (ICU). Pulmonary artery pressure (PA) pressures were measured at origin and at destination.

MEASUREMENTS AND MAIN RESULTS

Outcomes were changes from baseline in end-tidal CO, hemodynamic changes from baseline and pulmonary artery pressure changes from origin to destination. The average transport time between the 2 groups was not different: 5 minutes for patients ventilated by hand and 5.47 minutes for patients ventilated with a transport ventilator (p = 0.369 by 2-sided t-test). The difference in all measured changes in ETCO between hand-ventilated and machine-ventilated patients during transport was 2.74 mmHg (p = 0.013). The difference between operating room and ICU ETCO from each cohort was 1.31 mmHg (p = 0.067). The difference in PA measured at origin and destination was 0.783 mmHg (p = 0.622). All other hemodynamic variables were not different during transport.

CONCLUSIONS

Hand ventilation during transport was associated with greater change from baseline of ETCO compared to machine ventilation during transport after cardiac surgery, but this did not translate into any difference in hemodynamic changes upon arrival in ICU. A hemodynamic benefit of machine transport ventilation to cardiac patients was not demonstrated.

摘要

目的

心脏手术后患者在转运过程中通过手动或使用转运呼吸机进行通气的血流动力学后果尚未见报道。作者推测,在心脏手术后患者转运期间,袋 - 面罩通气会改变呼气末二氧化碳(ETCO)及血流动力学参数。

设计

一项前瞻性随机试验。

地点

一所大学附属的三级护理医院。

参与者

心脏手术患者。

干预措施

36例患者被随机分为手动通气组或机器通气组。在转运前、转运期间每2分钟以及到达重症监护病房(ICU)时,测量这些患者的血流动力学变量,包括血压、心率、外周血氧饱和度和呼气末二氧化碳(ETCO)。在出发地和目的地测量肺动脉压(PA)。

测量指标及主要结果

结果指标为呼气末二氧化碳相对于基线的变化、血流动力学相对于基线的变化以及肺动脉压从出发地到目的地的变化。两组之间的平均转运时间无差异:手动通气患者为5分钟,使用转运呼吸机通气的患者为5.47分钟(双侧t检验,p = 0.369)。在转运期间,手动通气和机器通气患者之间所有测量的呼气末二氧化碳变化差异为2.74 mmHg(p = 0.013)。每个队列中手术室和ICU的呼气末二氧化碳差异为1.31 mmHg(p = 0.067)。出发地和目的地测量的肺动脉压差异为0.783 mmHg(p = 0.622)。在转运期间,所有其他血流动力学变量无差异。

结论

与心脏手术后转运期间的机器通气相比,转运期间的手动通气与呼气末二氧化碳相对于基线的更大变化相关,但这并未转化为到达ICU时血流动力学变化的任何差异。未证明机器转运通气对心脏患者有血流动力学益处。

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